677704-73-3

Upstream product

• 677704-72-2 3-(4-methyl-piperazin-1-yl)-5-trifluoromethyl-benzonitrile 
• 109-01-3 1-methyl-piperazine 
• 149793-69-1 3-fluoro-5-trifluoromethyl-benzonitrile 
• 677704-68-6 4-(2,4-dimethyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzonitrile 

Downstream Products

• 677704-48-2 N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzamide 
• 1219947-35-9 N-{5-[4-(1,5-dimethyl-1H-pyrazol-4-yl)-1,2,3-triazol-1-yl]-6-methyl-pyridin-3-yl}-3-(4-methyl-piperazin-1-yl)-5-trifluoromethyl-benzamide 
• 1620069-08-0 (S)-N-(3-(1-(2-((2-hydroxypropyl)amino)pyrimidin-4-yl)-1H-imidazole-2-carbonyl)phenyl)-3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzamide 
• 1620068-81-6 (S)-N-(3-((1-(2-((2-hydroxypropyl)amino)pyrimidin-4-yl)-1H-imidazol-2-yl)methyl)phenyl)-3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzamide 
• 1353644-05-9 3-(4-methylpiperazin-1-yl)-N-(3-((2-oxoindolin-6-yl)amino)phenyl)-5-(trifluoromethyl)benzamide 
• 1292281-76-5 N-(5-amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-2-methyl-5-(3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzamido)benzamide 
• 1021531-40-7 N-[4-methyl-3-(7-methyl-2-oxo-1-phenyl-1,2-dihydro-[1,6]naphthyridin-3-yl)-phenyl]-3-(4-methyl-piperazin-1-yl)-5-trifluoromethyl-benzamide 
• 1024583-64-9 C₃₁H₃₂F₃N₇O₃S 

Relevant academic research and scientific papers

AZAINDOLE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES

The present invention relates to compounds of the following formula (I) and/or the pharmaceutically acceptable addition salts, solvates, enantiomers, diastereoisomers thereof, as well as mixtures thereof. The subject matter of the present invention thus a

PROTEIN KINASE INHIBITORS

The present invention relates to compounds of the following formula (I) and/or the pharmaceutically acceptable addition salts, solvates, enantiomers, diastereoisomers thereof, as well as mixtures thereof. The subject matter of the present invention thus also includes the preparation of compounds of formula (I), their uses, in particular in the inhibition of protein kinases which are implicated for example in numerous diseases such as cancers or immune system disorders.

AZAINDOLE DERIVATIVES AS MULTI KINASE INHIBITORS

The present invention relates to compounds of the following formula (I) and/or the pharmaceutically acceptable addition salts, solvates, enantiomers, diastereoisomers thereof, as well as mixtures thereof. The subject matter of the present invention thus also includes the preparation of compounds of formula (I), their uses, in particular in the inhibition of protein kinases which are implicated for example in numerous diseases such as cancers or immune system disorders.

NOVEL PYRIMIDINEAMIDE DERIVATIVES AND THE USE THEREOF

The invention relates to novel substituted N-(3-benzoylaminophenyl)-4-pyridyl-2-pyrimidinarnine derivatives, processes for the preparation thereof, pharmaceutical compositions containing same, the use thereof optionally in combination with one or more oth