677707-38-9 Usage
Chemical structure
The compound contains a purine base with an amine group and a fluoro substitution, as well as a phenylmethyl group with dimethoxy substitutions.
Biological role
Due to its structural similarity to purine nucleosides, it has potential pharmaceutical applications in various biological processes including DNA and RNA synthesis.
Altered activity
The addition of the fluoro and phenylmethyl groups could alter the biological activity and pharmacokinetics of 1H-Purin-6-amine, 8-[(2,5-dimethoxyphenyl)methyl]-2-fluoro-.
Pharmaceutical industry interest
It is an interesting target for further research and development in the pharmaceutical industry due to its potential applications and altered activity.
Check Digit Verification of cas no
The CAS Registry Mumber 677707-38-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,7,7,0 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 677707-38:
(8*6)+(7*7)+(6*7)+(5*7)+(4*0)+(3*7)+(2*3)+(1*8)=209
209 % 10 = 9
So 677707-38-9 is a valid CAS Registry Number.
677707-38-9Relevant academic research and scientific papers
Adenine derived inhibitors of the molecular chaperone HSP90 - SAR explained through multiple X-ray structures
Dymock, Brian,Barril, Xavier,Beswick, Mandy,Collier, Adam,Davies, Nicholas,Drysdale, Martin,Fink, Alexandra,Fromont, Christophe,Hubbard, Roderick E.,Massey, Andrew,Surgenor, Allan,Wright, Lisa
, p. 325 - 328 (2007/10/03)
Multiple co-crystal structures of an adenine-based series of inhibitors bound to the molecular chaperone Hsp90 have been determined. These structures explain the observed SAR for previously described compounds and new compounds, which possess up to 8-fold
