677707-47-0Relevant academic research and scientific papers
Synthesis and tumor inhibitory activity of novel coumarin analogs targeting angiogenesis and apoptosis
Vijay Avin,Thirusangu, Prabhu,Lakshmi Ranganatha,Firdouse, Aiyesha,Prabhakar,Khanum, Shaukath Ara
, p. 211 - 221 (2014/03/21)
A sequence of coumarin analogs 5a-j was obtained by multi step synthesis from hydroxy benzophenones (1a-j). The in vitro antiproliferative effect of the title compounds was tested against Ehrlich ascites carcinoma (EAC) and Daltons lymphoma ascites (DLA)
Synthesis and evaluation of in vitro antimicrobial activity of novel 2-[2-(aroyl)aroyloxy]methyl-1,3,4-oxadiazoles
Girish,Khanum, Noor Fatima,Gurupadaswamy,Khanum, Shaukath Ara
, p. 330 - 335 (2014/06/09)
Synthetic pathway of the ten novel 2-[2-(aroyl)aroyloxy]methyl-1,3,4- oxadiazoles as new potential antimicrobial agents is illustrated. Intramolecular cyclization of 2-(2-aroylaryloxy) aceto hydrazides to 2-[2-(aroyl)aroyloxy] methyl-1,3,4-oxadiazoles was
Anti-tumor and proapoptotic effect of novel synthetic benzophenone analogues in Ehrlich ascites tumor cells
Prabhakar,Khanum, Shaukath Ara,Jayashree,Salimath, Bharathi P.,Shashikanth
, p. 435 - 446 (2007/10/03)
A series of substituted benzophenone analogues, (2-aroyl-4-methylphenoxy) acetamides 4a-e, have been synthesized via three-step synthesis sequence beginning with the 2-hydroxybenzophenones 1a-e in excellent yield. 1a-e on reaction with ethyl chloroacetate
Synthesis and antimicrobial study of novel heterocyclic compounds from hydroxybenzophenones
Khanum, Shaukath A.,Shashikanth, Sheena,Umesha,Kavitha
, p. 1156 - 1162 (2007/10/03)
The triazolothiadiazine analogues 6a-e were obtained via a multistep synthesis sequences beginning with the hydroxybenzophenones 1a-e. Hydroxybenzophenones on reaction with ethyl chloroacetate affords ethyl (2-aroylaryloxy)acetates 2a-e which on treatment
Microwave-Assisted Synthesis of 2-Amino and 2-Azetidinonyl 5-(2-Benzoyl-phenoxymethyl) 1,3,4-Oxadiazoles
Khanum, Shaukath Ara,Shashikanth,Sudha
, p. 37 - 42 (2007/10/03)
A simple high yielding method for the integration of heterocyclic rings viz. 1,3,4-oxadiazole and azetidin-2-one at the benzophenone nucleus has been developed starting from substituted 2-hydroxybenzophenones, and by using mild conditions, wet solid surfa
Synthesis and anti-inflammatory activity of benzophenone analogues
Khanum, Shaukath A.,Shashikanth, Sheena,Deepak
, p. 211 - 222 (2007/10/03)
A series of substituted benzophenone analogues has been synthesized and evaluated as orally active anti-inflammatory agents with reduced side effects. The anti-inflammatory and ulcerogenic activities of the compounds were compared with naproxen, indometha
