58600-95-6

Basic information

• Product Name: 4-Methoxybenzoesure-4-methylphenylester
• Synonyms: 4-Methoxybenzoesure-4-methylphenylester
• CAS NO: 58600-95-6
• Molecular Formula: C₁₅H₁₄O₃
• Molecular Weight: 242.26986
• Mol File: 58600-95-6.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Methoxybenzoesure-4-methylphenylester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxybenzoesure-4-methylphenylester(58600-95-6)
• EPA Substance Registry System: 4-Methoxybenzoesure-4-methylphenylester(58600-95-6)

Safety Data

• Hazardous Substances Data: 58600-95-6(Hazardous Substances Data)

Upstream product

• 106-44-5 p-cresol 
• 201230-82-2 carbon monoxide 
• 696-62-8 para-iodoanisole 
• 849-83-2 bis(4-methoxybenzoyl) peroxide 
• 53271-44-6 S-(4-methylphenyl) thio(4-methoxybenzoate) 
• 140-39-6 1-acetoxy-4-methylbenzene 
• 100-09-4 4-methoxybenzoic acid 
• 15226-74-1 dicobalt octacarbonyl 
• 6343-26-6 1-(4-Methoxybenzoyl)pyrrolidine-2,5-dione 
• 5720-05-8 4-methylphenylboronic acid 
• 24056-08-4 N-methoxy-4-methoxylbenzamide 
• 50978-45-5 3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide 
• 100-07-2 4-methoxy-benzoyl chloride 
• 15088-73-0 4-methoxybenzoic dithioperoxyanhydride 

Downstream Products

• 26880-96-6 2-hydroxy-4'-methoxy-5-methyl-benzophenone 
• 677707-47-0 ethyl [2-(4-methoxybenzoyl)-4-methylphenoxy]acetate 
• 725744-71-8 [2-(4-methoxy-benzoyl)-4-methyl-phenoxy]-acetic acid 

Relevant articles and documents

Transition-Metal-Free DMAP-Mediated Aromatic Esterification of Amides with Organoboronic Acids

A new, transition-metal-free, effective method for aromatic esterification of amides with organoboronic acids has been developed. A wide range of benzoate derivatives were obtained with yields ranging from moderate to good. The catalytic reaction shows a broad substrate scope and excellent functional group tolerance. Conceptually, DMAP mediates the reaction and is crucial for this transformation.

Electrodimerization of N-Alkoxyamides for Zinc(II) Catalyzed Phenolic Ester Synthesis under Mild Reaction Conditions

An electrochemical On-Off method for phenolic ester synthesis from N-alkoxyamides has been reported. This one-pot protocol begins with rapid and selective electrodimerization of the amide using n-Bu4NI (TBAI) as an electrocatalyst. The reaction proceeds further in the absence of current via Zn catalyzed C?N bond activation of the amide dimer followed by its coupling with phenol to form the ester. The present methodology is ligand-free and takes place under mild reaction conditions. This transformation incorporates a wide variety of phenols and amide substrates leading to the formation of functionalized esters highlighting its versatility. (Figure presented.).

Diacyl Disulfide: A Reagent for Chemoselective Acylation of Phenols Enabled by 4-(N,N-Dimethylamino)pyridine Catalysis

A general and excellent acylation reagent, diacyl disulfide, was uncovered for efficient ester formation enabled by DMAP (4-(N,N-dimethylamino)pyridine) catalysis. This protocol offered a promising synthetic platform on site-selective acylation of phenolic and primary aliphatic hydroxyl groups, which greatly expanded the realm of protecting group chemistry. The importance of the reagent was also reflected by its excellent moisture tolerance, high efficiency, and potential in synthetic chemistry and biologically meaningful natural product modification.