677729-43-0Relevant academic research and scientific papers
Synthesis of 3,4,4′- and 2′,3,4-triaminodiphenyl ethers
Pilyugin,Mikhailyuk,Kiseleva,Kuznetsova,Chikisheva,Kosareva
, p. 1105 - 1109 (2003)
Procedures were developed for preparing 3,4,4′- and 2′,3,4-triaminodiphenyl ethers by the reaction of 4-acetylaminophenol with, respectively, 4-nitro- or 2-nitrochlorobenzene, followed by nitration of the resulting 4-acetylamino-4′- or -2′-nitrodiphenyl ether, hydrolysis of the product, 4-acetylamino-3,4′- or -2′,3- dinitrodiphenyl ether, and reduction of 4-amino-3,4′- or -2′-3-dinitrodiphenyl ether.
Synthesis of methyl 5(6)-(4-aminophenoxy)-and 5(6)-(2-aminophenoxy)-2- benzimidazolyl carbamates and their biological properties
Pilyugin,Mikhailyuk,Kosareva,Chikisheva,Kiseleva,Kuznetsova,Vorobyeva,Klimakova
, p. 1154 - 1160 (2007/10/03)
A procedure was developed for preparation of methyl 5(6)-(4-aminophenoxy)- and 5(6)-(2-aminophenoxy)-2-benzimidazolyl carbamates by reaction of 3,4,4′-triaminodiphenyl or 3,4,2′-triaminodiphenyl ethers respectively with methyl cyanocarbamate in water solution in the presence of 7-10 molar excess of acetic acid. The helminthicidal properties, embryotoxicity, and overall toxicity of compounds obtained were estimated.
