67775-93-3Relevant academic research and scientific papers
Copper-catalyzed rearrangement of (Z)-propynal hydrazones via N-N bond cleavage
Nakamura, Itaru,Shiraiwa, Naozumi,Kanazawa, Ryo,Terada, Masahiro
scheme or table, p. 4198 - 4200 (2010/11/19)
Propynal hydrazones are successfully converted to the corresponding 3-aminoacrylonitriles in the presence of copper catalysts in good to high yields. As an example, (Z)-N-(hex-2-ynylidene)morpholin-4-amine reacted in the presence of 10 mol % Cu(OAc)2 in acetonitrile at 25 °C to afford (E)-3-morpholinohex-2-enenitrile ((E)-2 h) in 77% yield via C-N bond formation and subsequent β-elimination involving cleavage of N-N and C-H bonds.
Sulfinyl Homo- and Hetero-Dienes from Sulfenic Acids: An Approach Towards Six-membered Nitrogen Heterocycles in Enantiomerically Pure Form
Aversa, Maria C.,Barattucci, Anna,Bilardo, Maria C.,Bonaccorsi, Paola,Giannetto, Placido
, p. 2241 - 2248 (2007/10/03)
Two different synthetic pathways are presented that provide access to enantiopure sulfinyl hydrazones; in both addition of sulfenic acid/unsaturation represents the crucial step of the procedure. The obtained results are discussed in terms of regioselecti
