677757-95-8Relevant academic research and scientific papers
Synthesis of enantiomeric-pure cyclohexenyl nucleoside building blocks for oligonucleotide synthesis
Gu, Ping,Griebel, Carsten,Van Aerschot, Arthur,Rozenski, Jef,Busson, Roger,Gais, Hans-Joachim,Herdewijn, Piet
, p. 2111 - 2123 (2007/10/03)
Lipases were used for the resolution of (±) (4aR, 7R, 8aS)-2-phenyl-4a,7,8,8a-tetrahydro-4H-1,3-benzodioxine. This separation was carried out on preparative scale and used for the synthesis of eight phosphoramidites of cyclohexenyl nucleosides (D- and L-series).
