677757-88-9

Upstream product

• 108-22-5 Isopropenyl acetate 
• 108-05-4 vinyl acetate 

Downstream Products

• 328926-84-7 (L)-2-phenyl-4a,7,8,8a-tetrahydro-4H-1,3-benzodioxin-7-ol 
• 677757-94-7 N-(9-{5-hydroxy-4-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-cyclohex-2-enyl}-9H-purin-6-yl)-benzamide 
• 677758-08-6 1-{(1R,4S,5R)-5-Hydroxy-4-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-cyclohex-2-enyl}-5-methyl-1H-pyrimidine-2,4-dione 
• 677757-95-8 9-(2-phenyl-4a,7,8,8a-tetrahydro-4H-benzo[1,3]dioxin-7-yl)-9H-purin-6-ylamine 
• 677758-07-5 5-methyl-1-(2-phenyl-4a,7,8,8a-tetrahydro-4H-benzo[1,3]dioxin-7-yl)-1H-pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Enzymatic resolution and base pairing properties of D- and L-cyclohexenyl nucleic acids (CeNA)

An enzymatic transesterification reaction afforded large scale resolution of the cyclohexenol precursor needed for preparation of both series of CeNA building blocks. CeNA oligos of "D-like" chirality display a strong and selective interaction with RNA, w

Synthesis of enantiomeric-pure cyclohexenyl nucleoside building blocks for oligonucleotide synthesis

Lipases were used for the resolution of (±) (4aR, 7R, 8aS)-2-phenyl-4a,7,8,8a-tetrahydro-4H-1,3-benzodioxine. This separation was carried out on preparative scale and used for the synthesis of eight phosphoramidites of cyclohexenyl nucleosides (D- and L-series).