67778-10-3Relevant academic research and scientific papers
PROCESS FOR PREPARING 3-ALKYL-7,7,9,9-TETRAMETHYL-1,3,8-TRIAZASPIRO[4,5]DECANE DERIVATIVE
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Page/Page column 11, (2008/12/08)
A process for preparing a 3-alkyl-7,7,9,9-tetramethyl-1,3,8-triazaspiro[4,5]decane derivative of the formula (IV) wherein R1 represents for example hydrogen and R2 represents a C6-C18 alkyl group; which comprises reacting a 7,7,9,9-tetramethyl-1,3,8-triazaspiro[4,5]decane derivative of the formula (I) wherein R1 has the same meaning as defined above, or a salt thereof with a base; using an alkylating agent of the formula (II) R2-X wherein R2 has the same meaning as defined above and X represents an elimination group; in an inert solvent in the presence of a quaternary ammonium salt of the formula (III) (R3)4N+ Y- wherein R3 independently represents a radical selected from the group consisting of an alkyl group and an aralkyl group, and Y- represents an anion; and a base.
