67800-61-7Relevant articles and documents
Immobilization of lipase from Burkholderia cepacia into calcium carbonate microcapsule and its use for enzymatic reactions in organic and aqueous media
Fujiwara, Masahiro,Shiokawa, Kumi,Yotsuya, Koji,Matsumoto, Kazutsugu
, p. 94 - 100 (2014/12/10)
We disclosed a useful procedure for the immobilization of a lipase from Burkholderia cepacia based on its encapsulation into vaterite calcium carbonate microcapsule. The immobilized enzyme had an adequate activity for the hydrolysis of 4-nitrophenyl aceta
Preparation of optically active 1,2-diol monotosylates by enzymatic hydrolysis
Shimada, Yasutaka,Sato, Hiroshi,Minowa, Shinji,Matsumoto, Kazutsugu
, p. 367 - 370 (2008/04/01)
An easy preparation of optically active 1,2-diol monotosylate derivatives by enzymatic hydrolysis is disclosed. Lipase PS (Burkholderia cepacia) catalyzes the hydrolysis of racemic 2-acetoxyhexyl tosylate with excellent enantioselectivity to afford the corresponding optically active compounds. In this reaction, a unique temperature effect is observed. After optimizing the reaction conditions, this procedure is widely applicable to the practical preparation of both enantiomers of various optically active compounds with high ee. Georg Thieme Verlag Stuttgart.
A Convenient Chemoenzymatic Synthesis of (R)- and (S)-(Chloromethyl)oxirane
Chen, Ching-Shih,Liu, Yeuk-Chuen,Marsella, Michael
, p. 2559 - 2561 (2007/10/02)
(R)- and (S)-1-Chloro-3-tosyloxypropan-2-ol have been prepared by biocatalysed enantioselective esterification in hexane, and in turn could be readily converted into optically active (chloromethyl)oxirane in high yield.