67813-05-2

Upstream product

• 1666-13-3 diphenyl diselenide 
• 292638-85-8 acrylic acid methyl ester 
• 645-96-5 Benzeneselenol 
• 23974-72-3 sodium phenylselenide 
• 5029-66-3 methyl 3-iodopropanoate 

Downstream Products

• 124006-32-2 (S)-N-(tert-Butoxycarbonyl)proline 1,2-dideuterio-3-(phenylselenenyl)propyl ester 
• 344765-65-7 4-(3-phenylselanyl-propyl)-hepta-1,6-dien-4-ol 
• 344765-71-5 1-(3-phenylselanyl-propyl)-cyclopent-3-enol 
• 124006-31-1 1,1-Dideuterio-3-(phenylselenenyl)propanol 

Relevant academic research and scientific papers

A simple zinc-mediated method for selenium addition to michael acceptors

In this work, we focused our attention on seleno-Michael type reactions. These were performed using zinc-selenolates generated in situ from diphenyl diselenide 1, 1,2-bis(3-phenylpropyl)diselenide 30, and protected selenocystine 31 via an efficient biphas

Direct biocatalysed synthesis of first sulfur-, selenium- and tellurium- containing l-ascorbyl hybrid derivatives with radical trapping and GPx-like properties

6-O-l-Ascorbyl selenoesters, thioesters and telluroesters can be efficiently and directly prepared from l-ascorbic acid and suitable functionalised chalcogenoesters through lipase-catalysed transesterification reactions. Novel synthesised l-ascorbyl deriv

Simple cleavage of diorganyl diselenides with NaBH4/PEG-400 and direct Michael addition to electron-deficient alkenes

Nucleophilic species of selenium were generated in situ from the reaction of diorganyl diselenide with NaBH4 in PEG-400 as solvent and selectively added to several α,β-unsaturated ketones, esters, acid, and nitrile. By this simple procedure, ch

β-Cyclodextrin-promoted addition of benzeneselenol to conjugated alkenes in water

For the first time, a mild and efficient procedure was developed for the conjugate addition of α,β-unsaturated compounds to benzeneselenol providing β-(phenylseleno)-substituted compounds (Scheme). The reaction was promoted by β-cyclodextrin, proceeded in

A convenient synthesis of β-phenylselenocarbonyl compounds by In-TMSCL promoted cleavage of diphenyl diselenide and subsequent michael addition

A simple and convenient procedure has been developed for the synthesis of β-phenylselenocarbonyl compounds by a one-pot reaction of diphenyl diselenide and α,β-unsaturated ketones, aldehydes, esters and nitriles in the presence of indium metal-trimethylsilyl chloride under sonication. Presumably, the In-TMSCl reagent system reacts with diphenyl diselenide to form an intermediate, PhSeSiMe3, which then undergoes Michael addition with the α,β-unsaturated carbonyl compounds to produce the products.

CeCl3/Sm system induced reductive cleavage of the Se-Se bond in diaryl diselenides: A novel method for the synthesis of β-selenoesters and β-selenonitriles

The Se-Se bond in diselenides was reduced by CeCl3/Sm system to produce selenolate anions, which react with α,β-unsaturated esters or α,β-unsaturated nitriles to afford β-selenoesters and β-selenonitriles, respectively.

Zn/Zrcl4 system induced reductive cleavage of the Se-Se bond in diaryl diselenides: A novel method for the synthesis of β-selenoesters and β-selenonitriles

The Se-Se bond in diselenides was reduced by Zn/ZrCl4 to produce selenolate anions, which react with α,β-unsaturated esters or α,β-unsaturated nitriles to afford β-selenoesters and β-selenonitriles, respectively.

Rapid and precise preparation of reactive benzeneselenolate solutions by reduction of diphenyl diselenide with hydrazine-sodium methanolate

Solutions of sodium benzeneselenolate sufficiently reactive to effect 'aromatic substitution and ester dealkylation are prepared in DMSO or NMP from diphenyl diselenide and hydrazine hydrate by titration with methanolic sodium methanolate.

An effective synthesis of β- selenium and β-tellurium carbonyl compounds via reaction of diaryldiselenides or diarylditellurides with α,β- unsaturated carbonyl compounds induced by low-valent titanium

β-Selenium and β-tellurium carbonyl compounds have been prepared in good yield by reaction of diaryldiselenides or diarylditelluride with α,β- unsaturated carbonyl compounds induced by TiCl4 / Sm/THF system under mild reaction conditions.

Reductive Cleavage of the Se-Se Bond by the Sm-Me3SiCl-H2O System: Preparation of Unsymmetrical Phenyl Selenides

The reduction of diphenyl diselenide by the Sm-Me3SiCl-H2O system led to a selenide anion. This 'living' species reacted with organic halides, epoxides, α,β-unsaturated esters and α,β-unsaturated nitrtles to afford unsymmetrical phenylselenides in good yields under mild and neutral conditions.