678160-06-0

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 99333-00-3 (+)-(1R,6S,7S)-7-diphenyl-t-butylsiloxymethyl-8-oxabicyclo-<4.3.0>non-3-en-9-one 
• 99315-76-1 (5S)-5-(tert-butyldiphenylsiloxymethyl)-2(5H)-furanone 

Downstream Products

• 885218-45-1 (7-dimethylamino-2-oxo-2H-chromen-4-yl)-acetic acid 2-[2-(tert-butyl-diphenyl-silanyloxymethyl)-5-oxo-hexahydro-furo[2,3-b]furan-3-yl]-ethyl ester 
• 678160-22-0 1-[(2S,3S,3aR,5R,6aR)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-yl]-1-((1S,3aS,7aS)-4,4,7a-trimethyl-octahydro-inden-1-yl)-ethanol 
• 678159-96-1 tert-Butyl-{(2S,3R,3aR,5R,6aR)-5-methoxy-3-[1-((1R,3aS,7aS)-4,4,7a-trimethyl-octahydro-inden-1-yl)-vinyl]-hexahydro-furo[2,3-b]furan-2-ylmethoxy}-diphenyl-silane 
• 678160-11-7 [(2S,3S,3aR,5R,6aR)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-yl]-((1S,3aS,7aS)-4,4,7a-trimethyl-octahydro-inden-1-yl)-methanone 
• 678160-21-9 [(2S,3R,3aR,5R,6aR)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-yl]-((3aS,7aS)-4,4,7a-trimethyl-3a,4,5,6,7,7a-hexahydro-3H-inden-1-yl)-methanol 
• 678160-10-6 [(2S,3S,3aR,5R,6aR)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-yl]-((3aS,7aS)-4,4,7a-trimethyl-3a,4,5,6,7,7a-hexahydro-3H-inden-1-yl)-methanone 
• 678160-08-2 tert-Butyl-[(2S,3S,3aR,5R,6aR)-5-methoxy-3-(2-phenylselanyl-ethyl)-hexahydro-furo[2,3-b]furan-2-ylmethoxy]-diphenyl-silane 
• 876173-62-5 tert-Butyl-[(2S,3S,3aR,5R,6aR)-3-(2-iodo-ethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-2-ylmethoxy]-diphenyl-silane 
• 876173-61-4 2-[(2S,3S,3aR,5R,6aR)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-yl]-ethanol 
• 678160-09-3 tert-Butyl-((2S,3S,3aR,5R,6aR)-5-methoxy-3-vinyl-hexahydro-furo[2,3-b]furan-2-ylmethoxy)-diphenyl-silane 
• 678159-98-3 (2S,3S,3aR,5R,6aR)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-carbaldehyde 
• 876173-73-8 [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-yl]-(4,4,7a-trimethyl-3a,4,5,6,7,7a-hexahydro-3H-inden-1-yl)-methanol 
• 876173-74-9 [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-yl]-(4,4,7a-trimethyl-3a,4,5,6,7,7a-hexahydro-3H-inden-1-yl)-methanone 
• 876173-70-5 tert-butyl-[5-methoxy-3-(2-phenylselanyl-ethyl)-hexahydro-furo[2,3-b]furan-2-ylmethoxy]-diphenyl-silane 

Relevant academic research and scientific papers

Norrisolide: Total synthesis and related studies

A stereoselective synthesis of (+)-norrisolide is presented. This natural product belongs to a family of marine spongiane diterpenes the structure of which is characterized by a fused γ-lactone-γ-lactol ring system attached to a bicyclic hydrophobic core.

Stereoselective Total Synthesis of (+)-Norrisolide

In a convergent approach to the marine natural product (+)-norrisolide (1) the two bicyclic ring systems are coupled through the C9-C10 bond to assemble the carbon framework in a late stage of the synthesis. Other highlights of the synthetic strategy incl