67824-30-0

Basic information

• Product Name: 5-Phenyl[1,2,3]triazolo[1,5-c]quinazoline
• Synonyms: 5-Phenyl[1,2,3]triazolo[1,5-c]quinazoline
• CAS NO: 67824-30-0
• Molecular Formula: C₁₅H₁₀N₄
• Molecular Weight: 246.27
• Mol File: 67824-30-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Phenyl[1,2,3]triazolo[1,5-c]quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Phenyl[1,2,3]triazolo[1,5-c]quinazoline(67824-30-0)
• EPA Substance Registry System: 5-Phenyl[1,2,3]triazolo[1,5-c]quinazoline(67824-30-0)

Safety Data

• Hazardous Substances Data: 67824-30-0(Hazardous Substances Data)

Upstream product

• 67824-29-7 2-phenyl-4-(5-tetrazolyl)quinazoline 
• 16714-25-3 2-azidobenzaldehyde 
• 552-89-6 2-nitro-benzaldehyde 
• 100-52-7 benzaldehyde 
• 65185-68-4 (E)-2-bromo-β-nitrostyrene 

Downstream Products

• 51072-85-6 2-phenyl-1H-indole-3-carbonitrile 

Relevant articles and documents

Consecutive cycloaddition/SNAr/reduction/cyclization/oxidation sequences: A copper-catalyzed multicomponent synthesis of fused N-heterocycles

A highly efficient multicomponent domino protocol has been developed for the synthesis of 5-phenyl-[1,2,3]triazolo[1,5-c]quinazolines from simple and readily available (E)-1-bromo-2-(2-nitrovinyl)benzenes, aldehydes, and sodium azide. This elegant domino process involved consecutive [3 + 2] cycloaddition, copper-catalyzed SNAr, reduction, cyclization, and oxidation sequences. Notably, sodium azide acted as a dual nitrogen source in the construction of this novel fused N-heterocycle.