67850-42-4

Basic information

• Product Name: L-Tryptophan, N-[(4-methylphenyl)sulfonyl]-
• CAS NO: 67850-42-4
• Molecular Formula: C18H18N2O4S
• Molecular Weight: 358.418
• Mol File: 67850-42-4.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: L-Tryptophan, N-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Tryptophan, N-[(4-methylphenyl)sulfonyl]-(67850-42-4)
• EPA Substance Registry System: L-Tryptophan, N-[(4-methylphenyl)sulfonyl]-(67850-42-4)

Safety Data

• Hazardous Substances Data: 67850-42-4(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 88452-86-2 (2S)-N-para-toluenesulfonylaziridine-2-carboxylic acid 
• 64-17-5 ethanol 
• 75-89-8 2,2,2-trifluoroethanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 73-22-3 L-Tryptophan 

Downstream Products

• 79659-73-7 N-<(4-Methylphenyl)sulfonyl>tryptophan Methyl Ester 
• 324535-16-2 C₂₄H₂₁BN₂O₄S 
• 239076-90-5 (S)-4-benzyl-2-[(S)-2-(indol-3'-yl)-1-[N-(4-methylphenyl)sulfonylamino]ethyl]-2-oxazoline 

Relevant articles and documents

NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME

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Synthesis, Characterization, and Reactivity of an Ethynyl Benziodoxolone (EBX)-Acetonitrile Complex

The synthesis of a crystalline ethynyl-1,2-benziodoxol-3(1H)-one (EBX)-acetonitrile complex is described. EBX has been widely used as an active species for a variety of reactions; however, its high instability has so far prevented its isolation. The EBX-acetonitrile is self-assembled into a double-layered honeycomb structure through weak hypervalent iodine secondary interactions and hydrogen bonding. The N-ethynylation of a variety of sulfonamides using the EBX-acetonitrile complex as a substrate under mild conditions is also described.

Palladium-Catalyzed Modular Synthesis of Substituted Piperazines and Related Nitrogen Heterocycles

We report here a novel method for the modular synthesis of highly substituted piperazines and related bis-nitrogen heterocycles via a palladium-catalyzed cyclization reaction. The process couples two of the carbons of a propargyl unit with various diamine components to provide nitrogen heterocycles in generally good to excellent yields and high regio- and stereochemical control. (Chemical Equation Presented).