67853-01-4Relevant articles and documents
Combined Cardioprotective and Adipocyte Browning Effects Promoted by the Eutomer of Dual sEH/PPARγModulator
Hartmann, Markus,Bibli, Sofia-Iris,Tews, Daniel,Ni, Xiaomin,Kircher, Theresa,Kramer, Jan S.,Kilu, Whitney,Heering, Jan,Hernandez-Olmos, Victor,Weizel, Lilia,Scriba, Gerhard K. E.,Krait, Sulaiman,Knapp, Stefan,Chaikuad, Apirat,Merk, Daniel,Fleming, Ingrid,Fischer-Posovszky, Pamela,Proschak, Ewgenij
, p. 2815 - 2828 (2021/03/09)
The metabolic syndrome (MetS) is a constellation of cardiovascular and metabolic symptoms involving insulin resistance, steatohepatitis, obesity, hypertension, and heart disease, and patients suffering from MetS often require polypharmaceutical treatment.
NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE
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Page/Page column 55, (2011/04/18)
The present invention relates to synthetic studies of a novel thiophenediamine derivative having a urea structure and to finding pharmaceutical actions thereof. The present invention provides a compound represented by the following general formula (1) or
Highly chemoselective hydrogenation method using novel finely dispersed palladium catalyst on silk-fibroin: Its preparation and activity
Ikawa, Takashi,Sajiki, Hironao,Hirota, Kosaku
, p. 2217 - 2231 (2007/10/03)
A palladium-fibroin complex (Pd/Fib) was prepared by soaking silk-fibroin in MeOH solution of Pd(OAc)2 for 2 days (under Ar atmosphere) - 4 days (under air). Pd(OAc)2 was gradually absorbed by fibroin and the rapid reduction of fibroin conjugated Pd(OAc)2 proceeded with MeOH as a reductant at room temperature to be the Pd(0) complex. Pd/Fib catalyzed chemoselective hydrogenation of acetylenes, olefins and azides in the presence of aromatic ketones and aldehydes, halides, N-Cbz protective groups and benzyl esters which are readily hydrogenated using Pd/C or Pd/C(en) as a catalyst.