67878-15-3Relevant academic research and scientific papers
Studies related to in vivo C-H activation: Synthesis and influence of 8,8- and 11,11-dimethyl oleic and 11,11-dimethyl linoleic acids on Δ12- desaturation of C. sorokiniana
Poulain, Sophie,Noiret, Nicolas,Fauconnot, Laetitia,Nugier-Chauvin, Caroline,Patin, Henri
, p. 3595 - 3604 (1999)
The synthesis of three acids was achieved using the Wittig reaction in order to study their in vivo influence on the Δ12-desaturase of Chlorella sorokiniana. It was shown that the introduction of two methyls near the double bond prevent the desaturation of these exogenous acids while they seem to be accurately incorporated. This functionality could be of interest for the design of new thiaoleic acids as probes of the different oxidation processes.
DEOXYNOJIRIMYCIN DERIVATIVES AND METHODS OF THEIR USING
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, (2016/08/29)
The present application provide novel iminosugars and their use in treatment of viral infections, such as Dengue infection and Influenza A infection. The present inventors discovered certain deoxynojirimycin derivatives may be effective against one or more viruses, which may be, for example, a Dengue virus and/or a virus belonging to the Orthomyxoviridae family, such as an Influenza A virus. In particular, such deoxynojirimycin derivatives may be useful for treating a disease or condition caused by or associated with one or more viruses. In certain embodiments, the deoxynojirimycin derivatives may increase a survival rate or probability for a subject infected with one or more viruses, which may be, for example, a Dengue virus and/or a virus belonging to the Orthomyxoviridae family, such as an Influenza A virus.
