67879-20-3

Basic information

• Product Name: 2-ethyl-4-oxo-4H-1-benzopyran-4-one
• Synonyms: 2-ethyl-4-oxo-4H-1-benzopyran-4-one
• CAS NO: 67879-20-3
• Molecular Weight: 236.27
• Mol File: 67879-20-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-ethyl-4-oxo-4H-1-benzopyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethyl-4-oxo-4H-1-benzopyran-4-one(67879-20-3)
• EPA Substance Registry System: 2-ethyl-4-oxo-4H-1-benzopyran-4-one(67879-20-3)

Safety Data

• Hazardous Substances Data: 67879-20-3(Hazardous Substances Data)

Upstream product

• 64448-06-2 (N-phenyliminovinylidene)triphenylphosphorane 
• 118-93-4 o-hydroxyacetophenone 
• 10147-11-2 propargyl benzene 
• 21615-34-9 2-Methoxybenzoyl chloride 
• 57938-89-3 1-(2-hydroxy-phenyl)-4-phenyl-butane-1,3-dione 
• 101-97-3 Ethyl 2-phenylethanoate 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 51685-51-9 2-benzoyl-1-benzopyran-4-one 
• 82381-48-4 2-((Z)-3-Hydroxy-1-isobutyl-4-phenyl-but-1-enyl)-phenol 
• 148403-83-2 ethyl 3-(2-chromonyl)-3-phenylpyruvate 
• 130984-36-0 2,3-dihydro-2-(phenylmethyl)-4H-1-benzopyran-4-one 
• 148403-79-6 4-(p-chlorophenyl)-5-phenyl-1,3,3a,4,11a,11b-hexahydro-3H-furo<3,4-a>xanthene-1,3,11-trione 

Relevant articles and documents

Unified Approach to (Thio)chromenones via One-Pot Friedel-Crafts Acylation/Cyclization: Distinctive Mechanistic Pathways of β-Chlorovinyl Ketones

A facile synthetic method to chromenones and thiochromenones has been developed using a one-pot Friedel-Crafts acylation of alkynes with suitably substituted benzoyl chlorides. This unified approach to (thio)chromenones is readily applicable to aryl- and alkylalkynes where the stereochemically well-defined β-chlorovinyl ketone intermediates undergo distinctively different cyclization pathways. The ready availability of both starting materials, alkynes and benzoyl chlorides, coupled with the experimental simplicity makes the current synthetic method to (thio)chromenones fast, efficient, and practical.

Ruthenium-NHC-catalyzed asymmetric hydrogenation of flavones and chromones: General access to enantiomerically enriched flavanones, flavanols, chromanones, and chromanols

Two to four! Readily available flavones and chromones were efficiently converted into four valuable chiral classes of O-heterocycles - flavanones, chromanones, flavanols, and chromanols - by means of an enantioselective Ru/NHC-catalyzed hydrogenation process (see scheme; NHC=N-heterocyclic carbene, PCC=pyridinium chlorochromate). Copyright

Photolysis of 3-bromochroman-4-ones

Photolysis of 3-bromochroman-4-ones (1a-f) leads to debrominated chromanones (2a-f) and chromones (3a-f) as major products. Their formation is accounted for in terms of primary cleavage of the carbon halogen bond to give α-carbonyl radicals (I) and/or cations (II). In the case of the 2,2-disubstituted compounds (1d-f), intermediates (II) undergo rearrangement with 1,2-shift of the phenyl or benzyl substituent prior to deprotonation. Minor by-products are the pentacyclic pyrone (4e) or 2-methylchromone (3a) (starting from 1e and 1f, respectively).