6788-34-7

Upstream product

• 14364-89-7 Gitoxigenin 3-O-monodigitalosideglucoside, or digitalinum verum 
• 1111-39-3 acetyldigitoxin 
• 17575-20-1 Digitoxigenin 3-O-bisdigitoxosideacetyldigilanidobioside, or lanatoside A 
• 27127-79-3 17α-digitoxigenin β-Gentiobiosyl-(1*4)-α-L-thevetoside 
• 114590-45-3 17α-digitoxigenin β-Cellobiosyl-(1*4)-α-L-thevetoside 
• 114590-46-4 17α-digitoxigenin β-D-apiosyl-(1*6)-β-D-glucosyl-(1*4)-α-L-thevetoside 
• 6877-82-3 Desglucouzarin 
• 41628-29-9 Uzarigenin 3-O-β-D-Glucopyranosyl (1-4)-β-D-Glucopyranoside 
• 71-63-6 digitoxin 
• 143-62-4 digitoxigenin 
• 143-62-4 (+)-digitoxigenin 

Downstream Products

• 143-62-4 3-epidigitoxigenin 
• 128701-09-7 digitoxigenin myristate 
• 128701-08-6 digitoxigenin palmitate 
• 128701-07-5 digitoxigenin stearate 
• 514-39-6 periplogenin 
• 514-39-6 3-epiperiplogenin 
• 6877-82-3 3-epidigitoxigenin β-D-glucoside 
• 18531-44-7 periplogenin β-D-glucoside 
• 6877-82-3 digitoxigenin β-D-glucoside 
• 20231-81-6 3-epidigitoxigenin β-D-gentiobioside 
• 2287-95-8 3β,14-dihydroxy-5β,14β-card-20(22)-enolide 3-(3-carboxypropanoate) 

Relevant academic research and scientific papers

BIOTRANSFORMATION OF DIGITOXIGENIN BY CELL SUSPENSION CULTURES OF STROPHANTHUS DIVARICATUS

Eight compounds, including a new compound (3-epi-17βH-gitoxigenin) were isolated as biotransformation products of digitoxigenin by cell suspension cultures of Strophanthus divaricatus.At the same time, three products were identified by TLC and HPLC. 16β-Hydroxylation and isomerization of the 17β-butenolide ring of digitoxigenin molecule were demonstrated using this cell suspension culture. Key Word Index - Strophanthus divaricatus; Apocynaceae; biotransformation; 16β-hydroxylation; isomerization of 17β-butenolide ring; cardenolides; digitoxigenin; 17βH-gitoxigenin; 3-epi-17βH-gitoxigenin.

BIOTRANSFORMATION OF DIGITOXIGENIN BY GINSENG HAIRY ROOT CULTURES

Five new compounds (three esters and two glycosides) and seven previously reported compounds were isolated as biotransformation products of digitoxigenin by ginseng hairy root cultures.The new esters and glycosides were elucidated as digitoxigenin stearate, digitoxigenin palmitate, digitoxigenin myristate, 3-epidigitoxigenin β-D-gentiobioside and digitoxigenin β-D-sophoroside using 1H and 13C NMR and FAB mass spectral data.Biotransformations involving esterification (of stearic acid, palmitic acid, myristic acid and lauric acid) and glycosylation (of gentiobiose and sophorose) of digitoxigenin have been demonstrated for the first time in the plant cell and tissue cultures.The hairy roots showed high glycosylation ability to the digitoxigenin molecule.