67895-03-8Relevant academic research and scientific papers
Antitubercular resorcinol analogs and benzenoid C-Glucoside from the roots of ardisia cornudentata
Chang, Chun-Po,Chang, Hsun-Shuo,Peng, Chien-Fang,Lee, Shiow-Ju,Chen, Ih-Sheng
, p. 60 - 65 (2011)
Bioassay-guided fractionation of the roots of Ardisia cornudentata Mez (Myrsinaceae) led to the isolation of three new compounds, 3-methoxy-2-methyl-5- pentylphenol (1), 3-methoxy-2-methyl-5-(1-ketopentyl)phenol (2), and cornudoside (3), together with twe
Synthesis and biological evaluation of coumarincarboxylic acids as inhibitors of gyrase B. L-rhamnose as an effective substitute for L-noviose
Ferroud, Didier,Collard, Jeannine,Klich, Michel,Dupuis-Hamelin, Claudine,Mauvais, Pascale,Lassaigne, Patrice,Bonnefoy, Alain,Musicki, Branislav
, p. 2881 - 2886 (2007/10/03)
A series of novobiocin-like coumarincarboxylic acids has been prepared bearing the L-rhamnosyl moiety as the sugar portion of the molecule. The similar DNA gyrase inhibitory activity of the novel class of coumarins to that of novobiocin demonstrates that L-rhamnose can effectively replace L-novoise. Introduction of alkyl side-chains at C-5 of coumarin leads to improved in vitro antibacterial properties in the novel series.
