Cas 678987-59-2,4-[5-(4-bromo-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-2-hydroxymethyl-benzenesulfonamide

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Check Digit Verification of cas no

The CAS Registry Mumber 678987-59-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,8,9,8 and 7 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 678987-59:
(8*6)+(7*7)+(6*8)+(5*9)+(4*8)+(3*7)+(2*5)+(1*9)=262
262 % 10 = 2
So 678987-59-2 is a valid CAS Registry Number.

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678987-59-2Relevant academic research and scientific papers

Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors

Singh, Sunil K.,Reddy, P. Ganapati,Rao, K. Srinivasa,Lohray, Braj B.,Misra,Rajjak, Shaikh A.,Rao, Yeleswarapu K.,Venkateswarlu

, p. 499 - 504 (2007/10/03)

Several chemical modifications in the N1-benzenesulfonamide ring of celecoxib are presented. The series with a hydroxymethyl group adjacent to the sulfonamide was found to be the most potent modification that yielded many compounds selectively active against COX-2 enzyme in vitro.

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