67901-82-0

Basic information

• Product Name: 7-HYDROXY-4-METHYL-1-INDANONE 97
• Synonyms: 7-HYDROXY-4-METHYL-1-INDANONE 97;4-Methyl-7-hydroxy-1-indanone;7-Hydroxy-4-Methyl-2,3-dihydro-1H-inden-1-one;4-Methyl-7-hydroxyindan-1-one;7-Hydroxy-4-methylindan-1-one;2,3-dihydro-7-hydroxy-4-methyl-1H-Inden-1-one;6-Hydroxy-2,3-dimethyl-benzaldehyde;7-Hydroxy-5-methyl-indan-1-one
• CAS NO: 67901-82-0
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.187
• Product Categories: C10;Carbonyl Compounds;Ketones
• Mol File: 67901-82-0.mol

Chemical Properties

• Melting Point: 109-112 °C(lit.)
• Boiling Point: 339.3 °C at 760 mmHg
• Flash Point: 144.4 °C
• Appearance: /
• Density: 1.25 g/cm³
• Vapor Pressure: 4.72E-05mmHg at 25°C
• Refractive Index: 1.614
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 10.59±0.20(Predicted)
• CAS DataBase Reference: 7-HYDROXY-4-METHYL-1-INDANONE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 7-HYDROXY-4-METHYL-1-INDANONE 97(67901-82-0)
• EPA Substance Registry System: 7-HYDROXY-4-METHYL-1-INDANONE 97(67901-82-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 2
• Hazardous Substances Data: 67901-82-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
7-HYDROXY-4-METHYL-1-INDANONE 97 is used as a key building block for the synthesis of various drugs and pharmaceuticals. Its unique chemical structure allows for the development of new and innovative medications, contributing to advancements in healthcare and medicine.
Used in Perfume and Flavor Industry:
7-HYDROXY-4-METHYL-1-INDANONE 97 is utilized as a component in the production of perfumes and flavors. Its ability to impart distinct scents and tastes makes it a valuable ingredient in creating a wide range of fragrances and flavorings for various consumer products.
Used in Dye and Pigment Manufacturing:
In the dye and pigment industry, 7-HYDROXY-4-METHYL-1-INDANONE 97 is employed for its color-producing properties. It is incorporated into the manufacturing process of various dyes and pigments, enhancing the color spectrum and quality of these products for use in textiles, paints, and other applications.
As a hazardous chemical, 7-HYDROXY-4-METHYL-1-INDANONE 97 necessitates proper handling and storage to ensure the safety of workers and the environment. Its diverse applications across different industries highlight its importance and potential for further development and innovation.

InChI:InChI=1/C10H10O2/c1-6-2-4-8(11)10-7(6)3-5-9(10)12/h2,4,11H,3,5H2,1H3

Upstream product

• 68293-33-4 4-methylphenyl 2-bromopropanoate 
• 106-44-5 p-cresol 
• 814-68-6 acryloyl chloride 
• 73057-23-5 3,7-dimethyl-1H-inden-4-ol 
• 104483-40-1 2,3-dihydro-1,4-dimethyl-1H-indene-1,7-diol 
• 13102-87-9 3-chloro-1-(2-hydroxy-5-methylphenyl)propan-1-one 
• 137937-52-1 3-methylphenyl 2-chloropropanoate 
• 94102-85-9 4-methylphenyl-3-chloropropanoate 
• 39513-75-2 6-methyl-4-chromanone 
• 86260-02-8 4'-methylphenyl 3-bromopropionate 

Downstream Products

• 16400-13-8 7-methylindan-4-ol 
• 67901-83-1 2,3-dihydro-7-methoxy-4-methyl-1H-inden-1-one 
• 6339-84-0 7-(2-diethylamino-ethoxy)-4-methyl-indan-1-one; hydrochloride 

Relevant articles and documents

Structure-based drug design of tricyclic 8H-indeno[1,2-d][1,3]thiazoles as potent FBPase inhibitors

With the goal of improving metabolic stability and further enhancing FBPase inhibitory activity, a series of tricyclic 8H-indeno[1,2-d][1,3]thiazoles was designed and synthesized with the aid of structure-based drug design. Extensive SAR studies led to th

Discovery of potent and orally active tricyclic-based FBPase inhibitors

With the aim of exploring the effect of tricyclic-based FBPase inhibitors in cells and in vivo, a series of prodrugs of tricyclic phosphonates was designed and synthesized. Introducing prodrug moieties into tricyclic-based phosphonates led to the discover

Anionic cyclizations of aromatic ester dithioacetals with facially biased α,β-unsaturated ketones

Cyclopent-2-enones bearing a plane-nonsymmetric oxygen function on C-4 reacted efficiently with anions derived from aromatic ester dithioacetals to provide annulated products in a highly diastereoselective fashion. Whereas the anion of a dimethoxy aromati

The Dimerisation of Some 4-Hydroxyindenes

The acid-catalysed dimerisation of the indenes (1)-(5), has been studied and a number of products isolated.The structure and stereochemistry of these compounds has been established by the use of crossed dimers, 13C-labelling, and 1H and 13C n.m.r. spectroscopy.

Synthetic Applications of Intramolecular Insertion in Arylcarbenes. VII. Aryl-Substituted Benzocycloalkenylidenes

A series of benzo-fused cyclic carbenes, bearing suitably located alkoxy substituents in the phenyl ring, has been generated in the gas phase and pyrolysed at 250 deg/0.002-0.40 mm.In all cases, carbene insertion into the adjacent C-H bond (Bamford-Stevens insertion) occurs, either exclusively or predominantly, with up to 35percent 1,5 C-H insertion in the alkoxy sidechain to form peri-fused tricyclic heterocycles.These results are rationalized in terms of geometrical and electronic effects.