67915-63-3

Usage

InChI:InChI=1/C13H21N/c1-3-4-6-9-12(2)14-13-10-7-5-8-11-13/h5,7-8,10-12,14H,3-4,6,9H2,1-2H3

Upstream product

• 56037-30-0 N-phenyl-(1-methylhexylidene)amine 
• 110-43-0 n-pentyl methyl ketone 
• 62-53-3 aniline 
• 104-15-4 toluene-4-sulfonic acid 
• 142-82-5 n-heptane 
• 98-95-3 nitrobenzene 
• 592-76-7 1-Heptene 
• 52390-72-4 2-Heptanol 
• 628-71-7 1-Heptyne 
• 5609-09-6 3-hepten-2-one 

Downstream Products

• 56037-30-0 N-phenyl-(1-methylhexylidene)amine 
• 157363-54-7 N-butyl-N-(1-methylhexyl)aniline 
• 157363-63-8 N-(1-methylhexyl)-N-propylaniline 

Relevant academic research and scientific papers

Construction of α-Alkylated Amines by Iridium Complex-Catalyzed One-Step Transfer Hydrogenation of C=C and C=N Bonds

Hydrogenation of C=C bond and reductive amination are important transformations utilized in chemistry. An environmentally friendly, efficient, and facile one-pot transfer hydrogenation of C=C bond of enones and reductive amination of C=N bond of imines are reported using iridium complex as catalysts and formic acid as hydrogen source in aqueous medium. In this catalytic system, a wide range of α-alkylated amines were obtained in excellent yields by one-pot transfer hydrogenation of C=C bond and reductive amination. The practical application of this protocol is characterized by gram-scale transformation.

Hemilabile N-heterocyclic carbene (NHC)-nitrogen-phosphine mediated Ru (II)-catalyzed N-alkylation of aromatic amine with alcohol efficiently

Based on the hemilability, a novel N-heterocyclic carbene (NHC)-nitrogen-phosphine ligand (1) was synthesized, and the combination of it with [Ru(COD)Cl2]n showed the high activity and selectivity with a low Ru loading of 0.1% for the N-alkylation of amine with alcohol. Especially, for these substrates with pyridine backbone, even if the catalyst loading was as low as 0.01%, good yields (81–95%) of the desired products were achieved.

Silver-catalyzed alkyne activation: The surprising ligand effect

An unexpected ligand effect was discovered in the silver(I)-catalyzed alkyne activation. For both aldehyde-alkyne-amine (A3) condensation and intermolecular alkyne hydroamination, the type B complex (P:Ag=1:1) effectively promoted the reaction, while no reaction occurred with either no ligand or excess ligands under the identical conditions.

Enantioselective organocatalytic reductive amination of aliphatic ketones by benzothiazoline as hydrogen donor

The chiral phosphoric acid-catalyzed enantioselective reductive amination of aliphatic ketones with aromatic amines was successfully achieved by the use of benzothiazoline as the hydrogen donor. Corresponding chiral aliphatic amines were obtained with exc

Catalyst-free one-pot reductive alkylation of primary and secondary amines and N,N-dimethylation of amino acids using sodium borohydride in 2,2,2-trifluoroethanol

A simple and convenient procedure for the reductive alkylation of primary and secondary amines and N,N-dimethylation of amino acids is described using sodium borohydride as a reducing agent in 2,2,2- trifluoroethanol without use of a catalyst or any other additive. The solvent can be readily recovered from reaction products in excellent purity for direct reuse. Georg Thieme Verlag Stuttgart - New York.

One-pot reductive amination of carbonyl compounds using sodium borohydride-amberlyst 15

A fast, efficient, and high-yielding method for the preparation of amines by reductive amination of aldehydes and ketones using sodium borohydride in the presence of Amberlyst 15 in tetrahydrofuran and under solvent-free conditions at room temperature is described.

One-pot reductive amination of carbonyl compounds using sodium borohydride-cellulose sulfuric acid

A fast, efficient, and high yielding method for the preparation of amines by reductive amination of aldehydes and ketones using sodium borohydride in the presence of cellulose sulfuric acid in EtOH and under solvent-free conditions at room temperature is described.

Direct reductive amination of carbonyl compounds using sodium borohydride-silica chloride

A simple and convenient procedure for reductive amination of aldehydes and ketones using sodium borohydride in the presence of silica chloride as an active, inexpensive, recoverable, and recyclable catalyst is described. The reactions were carried out with equimolar amounts of amine and carbonyl compound using silica chloride-sodium borohydride in THF at room temperature TUeBITAK.

Reductive amination of aldehydes and ketones using sodium borohydride in the presence of silica chloride under solvent-free conditions

A simple and convenient procedure for the preparation of amines from aldehydes and ketones with sodium borohydride activated by silica chloride as a catalyst under solvent-free conditions is described. A variety of aliphatic and aromatic aldehydes, ketones and amines when mixed with NaBH4/silica chloride at room temperature, afforded excellent yield of the corresponding amines.

Efficient and clean gold-catalyzed one-pot selective n-alkylation of amines with alcohols

Atom-efficient direct N-alkylation: An environmentally clean one-pot selective N-alkylation of amines with an equimolar amount of alcohols via a hydrogen autotransfer pathway was achieved over a titania-supported gold catalyst system in good to excellent yields without additive (see scheme).