679839-39-5

Basic information

• Product Name: 4-Bromo-2-fluoro-5-nitrobenzenecarbaldehyde
• Synonyms: 4-BroMo-2-fluoro-5-nitrobenzaldehyde;Benzaldehyde, 4-bromo-2-fluoro-5-nitro-
• CAS NO: 679839-39-5
• Molecular Formula: C₇H₃BrFNO₃
• Molecular Weight: 248.0060232
• Mol File: 679839-39-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 289.5±40.0 °C(Predicted)
• Appearance: /
• Density: 1.860±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-Bromo-2-fluoro-5-nitrobenzenecarbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-2-fluoro-5-nitrobenzenecarbaldehyde(679839-39-5)
• EPA Substance Registry System: 4-Bromo-2-fluoro-5-nitrobenzenecarbaldehyde(679839-39-5)

Safety Data

• Hazardous Substances Data: 679839-39-5(Hazardous Substances Data)

Usage

General Description

4-Bromo-2-fluoro-5-nitrobenzenecarbaldehyde is a chemical compound with the molecular formula C7H3BrFNO3. It is a yellow solid with a molecular weight of 238.01 g/mol. 4-Bromo-2-fluoro-5-nitrobenzenecarbaldehyde is categorized as an aldehyde and contains functional groups including bromine, fluorine, and nitro. It is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals and agrochemicals. 4-Bromo-2-fluoro-5-nitrobenzenecarbaldehyde is also known for its applications in research and development as a reagent for creating new chemical compounds. Additionally, it has potential uses in the field of medicinal chemistry for the development of new drugs and therapeutic agents.

Upstream product

• 57848-46-1 4-bromo-2-fluorobenzaldehyde 

Downstream Products

• 50593-24-3 1-methyl-1H-indazol-5-amine 
• 1403767-19-0 6-bromo-1-methyl-1H-indazol-5-ol 
• 1206800-24-9 6-bromo-5-(2-fluoro-4-nitrophenoxy)-1-methyl-1H-indazole 
• 1351811-41-0 C₂₃H₂₆N₆O₂S 
• 1351813-11-0 3-(5-(cyclohexylamino)-6-(1-methyl-1H-pyrazol-4-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazol-3-yl)benzenesulfonamide 
• 1351813-09-6 3-(5-amino-6-(1-methyl-1H-pyrazol-4-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazol-3-yl)benzenesulfonamide 
• 1351813-08-5 3-(6-(1-methyl-1H-pyrazol-4-yl)-5-nitro-1-((2-(trimethylsilyl)-ethoxy)methyl)-1H-indazol-3-yl)benzenesulfonamide 
• 1351813-02-9 6-bromo-5-nitro-1H-indazole 
• 679839-40-8 cis-4-bromo-2-(2,6-dimethylmorpholin-4-yl)-5-nitrobenzaldehyde 

Relevant articles and documents

COMPOUND SERVING AS IRAK INHIBITOR

The present disclosure relates a compound as an IRAK inhibitor. Specifically, the present disclosure provides a compound of formula I, or a cis-trans isomer, an optical isomer, a racemate, a pharmaceutically acceptable salt, a prodrug, a deuterated derivative thereof, a hydrate or a solvate thereof. The compounds disclosed herein have potent inhibitory effects on IRAK and thus have therapeutic effect on IRAK-related diseases.

PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS

Disclosed in the present application is a compound of formula (I) as defined herein as well as a pharmaceutical composition comprising said compound. Further disclosed in the present application is the use of such pharmaceutical compositions for treating diseases, namely inter alia for use in the treatment of cancer, metabolic, inflammatory, autoimmune and viral diseases. The compounds disclosed herein are inhibitors of MNK1 and/or MNK2 kinases.

HETEROCYCLIC DERIVATIVES AND USE THEREOF

A heterocyclic derivative represented by formula (I), or a pharmaceutically acceptable salt or a stereoisomer thereof, which has an inhibitory effect on the activation of STAT3 protein, and is useful for the prevention or treatment of diseases associated