679842-75-2

Upstream product

• 57294-86-7 (3-azidoprop-1-en-1-yl)benzene 
• 536-74-3 phenylacetylene 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 
• 57294-86-7 (E)-cinnamyl azide 
• 4392-24-9 Cinnamyl bromide 
• 2687-12-9 cinnamyl chloride 

Relevant academic research and scientific papers

Dinuclear Cu(I) Halides with Terphenyl Phosphines: Synthesis, Photophysical Studies, and Catalytic Applications in CuAAC Reactions

Several dinuclear terphenyl phosphine copper(I) halide complexes of composition [CuX(PR2Ar′)]2 (X = Cl, Br, I; R = hydrocarbyl, Ar′ = 2,6-diarylterphenyl radical), 1-5, have been isolated from the reaction of CuX with 1 equiv of the phosphine ligand. Most

Green synthesis of 1,2,3-triazoles via Cu2O NPs on hydrogen trititanate nanotubes promoted 1,3-dipolar cycloadditions

Cu2O nanoparticles supported on hydrogen trititanate nanotubes (Cu2O/HTNT) catalysts have been efficiently catalyzed the multicomponent synthesis of 1,2,3-triazoles in water at room temperature from different azide precursors, for example organic halides, sulfonates and anilines. The catalysts were synthesized by hydrothermal & wet-impregnation methods and was characterized by HR-TEM, EDS, XRD, XPS, N2-adsorption desorption and ICP-MS analysis. The catalyst could be recycled by centrifugation and reused up to seven cycles. The 1-benzyl-4-(4-chlorophenyl)-1H-1,2,3-triazole (25) structure was proven by single crystal X-ray diffraction studies.

Functionalized graphene oxide supported copper (I) complex as effective and recyclable nanocatalyst for one-pot three component synthesis of 1,2,3-triazoles

Efficient, one pot three-component reaction of alkyl halides, sodium azide with terminal alkynes can be catalyzed by functionalized graphene oxide with copper(I) under thermal conditions. A series of 1,4-disubstituted 1,2,3-triazoles were obtained by this one-pot strategy. The catalyst was prepared and characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), emission scanning electron microscopy (FE-SEM) and energy dispersive X-ray (EDX). The catalyst can be reused at least five times without significant deactivation.

Bio-waste corn-cob cellulose supported poly(hydroxamic acid) copper complex for Huisgen reaction: Waste to wealth approach

Corn-cob cellulose supported poly(hydroxamic acid) Cu(II) complex was prepared by the surface modification of waste corn-cob cellulose through graft copolymerization and subsequent hydroximation. The complex was characterized by IR, UV, FESEM, TEM, XPS, E

Ultrasound promoted facile one pot synthesis of triazole derivatives catalyzed by functionalized graphene oxide Cu(I) complex under mild conditions

A facile one pot three component reaction of alkyl halides, sodium azide with terminal alkynes can be catalyzed by functionalized graphene oxide copper (I) complex under ultrasonic irradiation at room temperature. In this protocol, the 1,4-disubstituted 1,2,3-triazoles were afforded as target pure products in excellent yields and short reaction times. The prepared catalyst has been characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction spectroscopy (XRD), Energy Dispersive X-ray (EDX) and field emission scanning electron microscopy (FE-SEM) techniques. Also, the catalyst is chemoselective and stable and can be reused several times without any appreciable loss of its catalytic activity.

Copper complexes bearing an NHC-calixarene unit: Synthesis and application in click chemistry

The synthesis of N-heterocyclic carbene (NHC) copper complexes supported by calix[4]arene is reported. Mono-substituted calix[4]arene was prepared through conventional procedures, followed by the attachment of an imidazolyl group to create the precursor o

Preparation and characterization of functionalized graphene oxide Cu (I) complex: A facile and reusable nanocatalyst for microwave assisted heterocyclization of alkyl halides with alkynes and sodium azide

In this research, preparation of functionalized graphene oxide copper (I) complex first involves a reaction of carboxylic groups on graphene oxide with the amino groups on 1,7-heptandiamine and isotoic anhydride, and subsequently treatment with copper iodide. The formed complex was characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction spectroscopy (XRD), energy dispersive X- ray (EDX) and field emission scanning electron microscopy (FE-SEM) techniques. 1,2,3-triazoles were synthesized from reaction of alkyl halides, alkynes and sodium azide catalyzed by functionalized graphene oxide copper (I) complex under microwave irradiation in excellent yields. This procedure eliminates the need to handle organic azides.

'Click' ligand for 'click' chemistry: (1-(4-methoxybenzyl)-1-H-1,2,3-triazol-4-yl)methanol (MBHTM) accelerated copper-catalyzed [3+2] azide-alkyne cycloaddition (CuAAC) at low catalyst loading

Readily accessible, cost effective, remarkably stable and easily tunable 1,2,3-triazole based ligand, (1-(4-methoxybenzyl)-1-H-1,2,3-triazol-4-yl)methanol (MBHTM) synthesized itself by 'click' chemistry shown to promote the dramatic rate enhancement of co

Solvent-free one-pot synthesis of 1,2,3-triazole derivatives by the 'Click' reaction of alkyl halides or aryl boronic acids, sodium azide and terminal alkynes over a Cu/Al2O3 surface under ball-milling

A one-pot procedure for the synthesis of 1,2,3-triazole derivatives by a three-component coupling of alkyl (benzyl) halides or aryl boronic acids, sodium azide and terminal alkynes over copper(ii) sulfate supported on alumina (Cu/Al2O3) under ball-milling in the absence of any solvent and additive has been developed. The product was isolated by simple washing of the crude reaction residue with ethanol followed by evaporation of the solvent. No chromatographic purification is required. The catalyst is recycled for subsequent reactions. The azides are produced in situ and thus this procedure avoids the handling of hazardous azides. This protocol offers broad scope for access to a variety of diversely substituted 1,2,3-triazoles. The use of no hazardous organic solvent, the use of ball-milling, and cost efficiency, recyclability of the catalyst up to eight runs without appreciable loss of activity and high yields of products make this procedure greener.

Well-defined diimine copper(I) complexes as catalysts in click azide-alkyne cycloaddition reactions

A series of 1,4-disubstituted 1,2,3-triazoles have been prepared in high yields while respecting the stringent Click criteria. In these reactions, highly stable pre-formed complexes bearing diimine ligands were used.