67985-14-2Relevant academic research and scientific papers
Enantioselective Phenol Coupling by Laccases in the Biosynthesis of Fungal Dimeric Naphthopyrones
Obermaier, Sebastian,Thiele, Wiebke,Fürtges, Leon,Müller, Michael
, p. 9125 - 9128 (2019/06/13)
Biaryl compounds are ubiquitous metabolites that are often formed by dimerization through oxidative phenol coupling. Hindered rotation around the biaryl bond can cause axial chirality. In nature, dimerizations are catalyzed by oxidative enzymes such as la
Biomimetic Synthesis of Polyketide Aromatics from Reaction of an Orsellinate Anion with Pyrones and a Pyrylium Salt
Leeper, Finian J.,Staunton, James
, p. 1053 - 1059 (2007/10/02)
Orsellinate anion (12) shows highly regioselective attack on pyrones (13), (22), and (30), and the products were simply converted into derivatives of the polyketides: toralacton (19), 6-hydroxymusizin (26), and eleutherinol (32); although reaction of the anion (12) with the pyrylium salt (33) is less selective, the minor product (34) can give derivatives of either alternariol (36) or rubrofusarin (37) in regiospecific biomimetic reactions.
ON THE REACTION OF ORSELLINIC ACID CARBANION WITH PYRYLIUM SALTS
Hoefle, Gerhard,Schneider, Guenther,Roeser, Karl
, p. 1633 - 1636 (2007/10/02)
From the reaction of methyldimethyl orsellinate anion 1 with the pyrylium salt 2 the isocumarin 5 was isolated in addition to the pyrones 3 and 4.Reaction intermediates could be trapped as pyridines 6 and 7.
