68-91-7 Usage
Definition
ChEBI: The (S)-camphorsulfonate salt of trimethaphan.
General Description
Trimethaphan camsylate,(+)-1,3-dibenzyldecahydro2-oxoimidazo[4,5-c]thieno[1,2-α]-thiolium 2-oxo-10-bornanesulfonate (1:1)(Arfonad), consists of white crystals or a crystalline powderwith a bitter taste and a slight odor. It is soluble inwater and alcohol but only slightly soluble in acetone andether. The pH of a 1% aqueous solution is 5.0 to 6.0.
Clinical Use
This ganglionic blocking agent is short acting and isused for certain neurosurgical procedures in which excessivebleeding obscures the operative field. Certain craniotomiesare included among these operations. The actionof the drug is direct vasodilation, and because of its transientaction, it is subject to minute-by-minute control.This fleeting action, however, makes it useless for hypertensivecontrol. The drug is ineffective when given orally.The usual route of administration is intravenous.Trimethaphan camsylate is indicated in the treatment ofhypertensive emergencies to reduce blood pressure rapidly.These emergencies may include pulmonary hypertensionassociated with systemic hypertension and acutedissecting aneurysm.
Check Digit Verification of cas no
The CAS Registry Mumber 68-91-7 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 6 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 68-91:
(4*6)+(3*8)+(2*9)+(1*1)=67
67 % 10 = 7
So 68-91-7 is a valid CAS Registry Number.
InChI:InChI=1/C22H25N2OS.C10H16O4S/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h1-6,8-11,19-21H,7,12-16H2;7H,3-6H2,1-2H3,(H,12,13,14)/q+1;/p-1