68006-83-7 Usage
Uses
Used in Research Applications:
2-AMINO-3-METHYL-9H-PYRIDO[2,3-B]INDOLE is used as a research compound for studying the mutagenic and carcinogenic effects of heterocyclic amines formed during cooking. It helps researchers understand the mechanisms of DNA damage and cancer development, as well as explore potential strategies for mitigating the harmful effects of these compounds in food.
Used in Food Safety and Public Health:
2-AMINO-3-METHYL-9H-PYRIDO[2,3-B]INDOLE is used as a biomarker for assessing the presence of mutagenic and carcinogenic heterocyclic amines in cooked food products. Monitoring the levels of MeAαC and other related compounds can help ensure food safety and minimize the risk of cancer associated with the consumption of cooked foods containing these harmful substances.
Safety Profile
Confirmed carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.
Check Digit Verification of cas no
The CAS Registry Mumber 68006-83-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,0,0 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 68006-83:
(7*6)+(6*8)+(5*0)+(4*0)+(3*6)+(2*8)+(1*3)=127
127 % 10 = 7
So 68006-83-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H11N3/c1-7-6-9-8-4-2-3-5-10(8)14-12(9)15-11(7)13/h2-6H,1H3,(H3,13,14,15)
68006-83-7Relevant academic research and scientific papers
Synthesis of Amino-Substituted α- And δ-Carbolines via Metal-Free [2 + 2 + 2] Cycloaddition of Functionalized Alkyne-Nitriles with Ynamides
Zhang, Jingyi,Guo, Meichao,Chen, Yajuan,Zhang, Shuangshuang,Wang, Xiao-Na,Chang, Junbiao
, p. 1331 - 1336 (2019/02/19)
A metal-free [2 + 2 + 2] cycloaddition of alkyne-cyanamides or ynamide-nitriles with ynamides is described for the efficient synthesis of amino-substituted α- and δ-carbolines. This novel methodology is environmentally friendly and allows for highly regioselective access to carboline derivatives in good to excellent yields with wide functional group tolerance.
