68008-72-0

Upstream product

• 2719-27-9 cyclohexanylcarbonyl chloride 
• 615-43-0 2-iodophenylamine 
• 38346-48-4 N-(2-imidazol-1-yl-phenyl)-formamide 
• 26286-54-4 1-(2-aminophenyl)imidazole 
• 98-89-5 Cyclohexanecarboxylic acid 
• 68007-72-7 N-<2-(imidazol-1-yl)phenyl>cyclohexanecarboxamide 

Relevant academic research and scientific papers

Synthesis of highly functionalized polycyclic quinoxaline derivatives using visible-light photoredox catalysis

A mild and facile method for preparing highly functionalized pyrrolo[1,2-a]quinoxalines and other nitrogenrich heterocycles, each containing a quinoxaline core or an analogue thereof, has been developed. The novel method features a visible-light-induced decarboxylative radical coupling of ortho-substituted arylisocyanides and radicals generated from phenyliodine(III) dicarboxylate reagents and exhibits excellent functional group compatibility. A wide range of quinoxaline heterocycles have been prepared. Finally, a telescoped preparation of these polycyclic compounds by integration of the in-line isocyanide formation and photochemical cyclization has been established in a three-step continuousflow system.

Synthesis of 4-substituted imidazo[1,2-a]quinoxalines

A concise approach to 4-substituted imidazo[1,2-a]quinoxalines 7 is described, starting from 1-fluoro-2-nitrobenzene (3). The high variability in the functionalization of the imidazo [1,2-a]quinoxaline-4-position is due to the easy introduction of these substituents by N-acylation in the second last step. WILEY-VCH Verlag GmbH, 1999.

Method for treating fungal infection in mammals with imidazo [1,2-a]quinoxalines

A method for treating a fungal infection in mammals which comprises administering to said mammals having a fungal infection a therapeutically effective amount of a 4-(substituted phenyl)imidazo[1,2-a]quinoxaline.

1-(2-Phenylureylene)imidazoles

A 1-(2-acylaminophenyl)imidazole of formula: STR1 wherein R2 is hydrogen or a radical bonded to the nitrogen by a carbon to nitrogen linkage and selected from the group consisting of aliphatic, cycloaliphatic, phenyl, substituted phenyl, fused bicyclic aryl, and monocyclic aryl substituted aliphatic groups.

1-(2-Acylaminophenyl)imidazoles

A 1-(2-acylaminophenyl)imidazole of formula: STR1 wherein R5 is hydrogen or an aliphatic, cycloaliphatic, phenyl, substituted phenyl, fused bicyclic aryl or monocyclic aryl substituted aliphatic group bonded to the carbonyl carbon through a carbon-to-carbon linkage. The compounds are useful as intermediates in the preparation of 4-substituted imidazo[1,2-a]quinoxalines.