680185-89-1Relevant academic research and scientific papers
GC–MS study of thermochemical conversion of guaifenesin in the presence of 1-butyl-3-methylimidazolium-based ionic liquids
Hamid, Sharifah Bee Abd,Khaligh, Nader Ghaffari,Sharifi, Mahdieh,Johari, Suzaimi
, p. 4007 - 4021 (2017/06/20)
Thermochemical conversion of guaifenesin was performed in the presence of 1-butyl-3-methylimidazolium tetrafluoroborate [BMIM][BF4] ionic liquid at 80?°C within 2?h. After evaluating the effect of different parameters, such as protic and nonpro
Exploration of l-proline-catalyzed α-aminoxylation of aldehyde to (s)-guaifenesin-related drug molecules
Panchgalle, Sharad P.,Kunte, Sunita S.,Chavan, Subhash P.,Kalkote, Uttam R.
experimental part, p. 1938 - 1946 (2011/06/26)
An efficient enantioselective synthesis of (S)-guaifenesin with >99% ee using L-proline-catalyzed α-aminoxylation of aldehyde as key step is described and explored for asymmetric syntheses of (S)-moprolol and (R)-methocarbamol.
