680195-78-2Relevant academic research and scientific papers
Correlation of hydrolysis and desilylation of 2-[(trimethylsilyl)methyl] acrylate derivatives in aqueous alkali solutions
Kuroda, Chiaki,Sunakawa, Takeshi,Muguruma, Yuichi
scheme or table, p. 888 - 896 (2009/03/11)
Hydrolysis and desilylation reaction of 2-[(trimethylsilyl)methyl]acrylate (=2-[(trimethylsilyl)methyl] prop-2-enoate) derivatives were studied to evaluate the effect of the presence/absence of a further conjugating substituent (Schemes 3 and 4 and Tables 1 and 2). The substrates having a nonconjugating substituent at the acrylate moiety were stable to dilute alkali conditions, and afforded simple hydrolysis products under concentrated alkali conditions. In contrast, both hydrolysis and desilylation occurred from the substrates bearing conjugated substituents at the acrylate skeleton. The difference in reactivity can be explained in terms of the stabilization of the intermediate anion.
(E)-selective synthesis of γ-substituted-β -(ethoxycarbonyl)allylsilanes utilising ethyl 2-diphenylphosphono-3-(trimethylsilyl)propionate. Improved synthesis of 11 membered carbocycle by a homo-Cope reaction
Suzuki, Hideyuki,Kuroda, Chiaki
, p. 310 - 312 (2007/10/03)
(E)-γ-Substituted-β-(ethoxycarbonyl)allylsilanes were selectively synthesised by Horner-Wadsworth-Emmons reaction utilising ethyl 2-diphenylphosphono-3-(trimethylsilyl)propionate.
