680231-64-5

Upstream product

• 680231-54-3 ((6R,7S)-8-oxo-6-phenyl-6,7,8,9-tetrahydro-5-oxa-9-aza-benzocycIohepten-7-yl)-carbamic acid tert-butyl ester 
• 96-32-2 bromoacetic acid methyl ester 

Downstream Products

• 893421-92-6 ((6R,7S)-7-tert-butoxycarbonylamino-8-oxo-6-phenyl-7,8-dihydro-6H-5-oxa-9-aza-benzocyclohepten-9-yl)-acetic acid 
• 680231-65-6 ((6R,7S)-7-amino-8-oxo-6-phenyl-7,8-dihydro-6H-5-oxa-9-aza-benzocyclohepten-9-yl)-acetic acid methyl ester 

Relevant academic research and scientific papers

NOVEL MOLECULAR PROBES

The present invention relates to novel molecular probes having the formula (I) (I) useful for the characterization, detection, localization and isolation of the γ-secretase enzyme.

NOVEL LACTAMS AND USES THEREOF

Compounds having the formula (I) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid ? protein production and neurological disorders such as Alzheimer's disease.. These compounds inhibit γ secretase and thereby inhibit the production of amyloid ? protein, thereby acting to prevent the formation of neurological deposits of amyloid protein.