68034-75-3

Usage

Uses

Used in Pharmaceutical Industry:
3-(3-IODOPHENYL)PROPIONIC ACID is used as a precursor in the synthesis of pharmaceutical products for the development of drugs intended to treat a variety of medical conditions. Its structural properties make it a valuable component in creating new medications.
Used in Research Applications:
In the research field, 3-(3-IODOPHENYL)PROPIONIC ACID is utilized as a starting material for the synthesis of intermediates, facilitating the exploration and creation of new chemical compounds and organic synthesis pathways.
Used in Organic Synthesis:
3-(3-IODOPHENYL)PROPIONIC ACID is employed as a building block in organic synthesis, contributing to the formation of complex organic molecules and aiding in the advancement of chemical research and development.

InChI:InChI=1/C9H9IO2/c10-8-3-1-2-7(6-8)4-5-9(11)12/h1-3,6H,4-5H2,(H,11,12)

Upstream product

• 41070-12-6 3-iodocinnamic acid 
• 121269-65-6 ethyl 3-(3-iodophenyl)propanoate 
• 2033-24-1 cycl-isopropylidene malonate 
• 696-41-3 m-iodobenzaldehyde 
• 555-68-0 m-Nitrocinnamic Acid 
• 10039-64-2 ethyl 3-(3-aminophenyl)propanoate 
• 1664-54-6 3-(3-aminophenyl)propionic acid 
• 7681-11-0 potassium iodide 
• 1664-56-8 m-aminocinnamic acid 
• 5396-71-4 ethyl 3-(3-nitrophenyl)acrylate 
• 57455-06-8 3-iodobenzylalcohol 

Downstream Products

• 121269-72-5 1-octanoyl-2-<3-(3-iodophenyl)propanoyl>-3-O-trityl-rac-glycerol 
• 1268000-11-8 N-(3-(meta-iodophenyl)propanoyl)glycine ethyl ester 

Relevant academic research and scientific papers

Structure-Guided Identification of DNMT3B Inhibitors

Methyltransferase 3 beta (DNMT3B) inhibitors that interfere with cancer growth are emerging possibilities for treatment of melanoma. Herein we identify small molecule inhibitors of DNMT3B starting from a homology model based on a DNMT3A crystal structure.

Selective alkyl ether cleavage by cationic bis(phosphine)iridium complexes

Catalysts capable of heterolytic silane activation have been successfully applied to the conversion of alkyl ethers to silyl ethers via C-O bond cleavage. The previously-reported cationic pincer-supported iridium complex for this transformation suffers fr

PYRROLE DERIVATIVE

A novel pyrrole derivative represented by the following formula (1) and a salt thereof: wherein R1 means substituted alkenyl, etc.; R2 means substituted benzoyl, etc.; and R3 to R5 each means hydrogen, alkyl, halogeno, etc. The derivative and salt have antidiabetic activity.

Protein-tyrosine phosphatase inhibitors and uses thereof

The present invention is directed to compounds of formula (I), or a pharmaceutically suitable salt or prodrug thereof, which are useful for the selective inhibition of protein tyrosine phosphatase-1B (PTP1B), and are useful for the treatment of disorders caused by overexpressed or altered protein tyrosine phosphatase 1B.

The effect of vinyl esters on the enantioselectivity of the lipase-catalysed transesterification of alcohols

The enantioselectivity of the lipase from Pseudomonas cepacia (PCL) in the transesterification of 2-phenyl-1-propanol 1 was studied using a series of vinyl 3-arylpropanoates as acyl donors. The most enantioselective transesterification reaction of the alcohol was attained by using vinyl 3-(p-iodophenyl)- or 3-(p-trifluoromethylphenyl)propanoates, with enantiomer ratios, E, of 116 and 138, respectively. Vinyl 3-phenylpropanoate was also effective for the resolution of 1 mediated by lipases from P. fluorescens and porcine pancreas and for the PCL-catalysed transesterification of several 2-phenyl-1-alkanols. The enantiomeric resolution of 1 was practically carried out by the first enantioselective transesterification using PCL and vinyl 3-(p-iodophenyl)propanoate to afford (R)-1 and then the enantioselective hydrolysis of the resultant ester to afford (S)-1.

Iodoaryl analogues of dioctanoylglycerol and 1-oleoyl-2-acetylglycerol as probes for protein kinase C

Analogues of dioctanoylglycerol (diC8) and 1-oleoyl-2-acetylglycerol (OAG) containing an iodoaryl group have been synthesized and shown to compete with [3H]phorbol dibutyrate ([3H]PDBu) for binding to protein kinase C in a crude rat brain preparation. Phorbol diesters have been shown to bind specifically to protein kinase C and the PDBu receptor has been copurified with protein kinase C activity. All three diacylglycerol analogues were comparable to OAG in binding affinity. In an assay of protein kinase C activation, the diC8 analogue was more active than the OAG analogues, thus demonstrating greater structural specificity under the conditions of this assay.