680594-42-7

Basic information

• Product Name: 2-[(5-{[(4-Methylphenyl)amino]methyl}-4-phenyl-4H-1,2,4-triazol-3-yl)thio]acetohydrazide
• Synonyms: 2-[(5-{[(4-Methylphenyl)amino]methyl}-4-phenyl-4H-1,2,4-triazol-3-yl)thio]acetohydrazide;2-[[5-[[(4-methylphenyl)amino]methyl]-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetohydrazide;2-[[5-[[(4-methylphenyl)amino]methyl]-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]ethanehydrazide;2-[[5-[[(4-methylphenyl)amino]methyl]-4-phenyl-1,2,4-triazol-3-yl]thio]acetohydrazide;2-((4-PHENYL-5-((P-TOLYLAMINO)METHYL)-4H-1,2,4-TRIAZOL-3-YL)THIO)ACETOHYDRAZIDE
• CAS NO: 680594-42-7
• Molecular Formula: C₁₈H₂₀N₆OS
• Molecular Weight: 368.456
• Mol File: 680594-42-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[(5-{[(4-Methylphenyl)amino]methyl}-4-phenyl-4H-1,2,4-triazol-3-yl)thio]acetohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(5-{[(4-Methylphenyl)amino]methyl}-4-phenyl-4H-1,2,4-triazol-3-yl)thio]acetohydrazide(680594-42-7)
• EPA Substance Registry System: 2-[(5-{[(4-Methylphenyl)amino]methyl}-4-phenyl-4H-1,2,4-triazol-3-yl)thio]acetohydrazide(680594-42-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 680594-42-7(Hazardous Substances Data)

Usage

Potential pharmaceutical properties

The compound may have applications in drug design and development due to its ability to interact with biological systems.

Thioacetohydrazide group

A functional group containing a硫 (sulfur) atom bonded to an acetohydrazide group.

Triazolyl ring

A heterocyclic ring with three nitrogen atoms and one carbon atom in a four-membered ring structure.

Substituted phenyl group

A benzene ring with a methyl group (-CH3) attached to the 4th carbon atom.

Further research

Necessary to fully understand the chemical and pharmacological properties of the compound and its potential uses in medicine.

Upstream product

• 92515-98-5 4-phenyl-1-(N-p-tolylamino)acetyl thiosemicarbazide 
• 92516-06-8 5-mercapto-4-phenyl-3-(N-p-tolylamino)methyl-1,2,4-triazole 
• 103-72-0 phenyl isothiocyanate 
• 482652-40-4 ethyl [4-phenyl-5-(N-p-tolylamino)methyl-1,2,4-triazol-3-yl]thioglycolate 
• 2350-99-4 2-[(4-methylphenyl)amino]acetohydrazide 

Relevant articles and documents

Synthesis of some functionalized arylaminomethyl-1,2,4-triazoles, 1,3,4-oxa- and thiadiazoles

Thiosemicarbazides undergo different cyclization reactions to give five membered heterocycles. The product of cyclization depends on the reagent used. This cyclization leads to the formation of 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole derivatives. The reaction of thioglycolyl hydrazide derivatives of the 1,2,4-triazole compounds was discussed. The activity against hepatitis B virus (HBV) has been tested.