680608-52-0Relevant academic research and scientific papers
Synthesis, in vitro urease inhibitory activity, and molecular docking studies of (perfluorophenyl)hydrazone derivatives
Khan, Momin,Ahad, Ghulam,Manaf, Abdul,Naz, Reshma,Hussain, Syed Roohul,Deeba, Farah,Shah, Sana,Khan, Ajmal,Ali, Majid,Zaman, Khair,Zafar, Salman,Salar, Uzma,Hameed, Abdul,Khan, Khalid Mohammed
, p. 873 - 883 (2019)
A series of (perfluorophenyl)hydrazone derivatives 1–27 were synthesized by the condensation reaction of (perfluorophenyl)hydrazine with a variety of benzaldehydes. Compounds were structurally characterized by various spectroscopic techniques. All compoun
Mass spectrometrical and quantum-chemical study of pentafluorophenylhydrazones
Bortňák, Du?an,Pecher, Daniel,Végh, Daniel,Breza, Martin,Miku?, Peter,Milata, Viktor
, (2020/10/06)
Twenty-one pentafluorphenylhydrazones have been analyzed by means of tandem mass spectrometry (ESI MS/MS) conditions to compare their fragmentations with those ones obtained from quantum-chemical calculations of the hydrazone moiety depending on the substitution from the aldehyde site. The hydrazone N–N bond is disrupted under such conditions, and these results are in accordance with the facts that an electron-rich particle, such as an anion and or radical in a solution, can cause this disruption and simultaneous defluorination in para-position of the hydrazone part of the molecule.
Enhancers of protein degradation
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Page/Page column 16, (2011/04/14)
The present invention relates to compounds suitable for modulating huntingtin protein processing and useful for treating or preventing huntingtin-related disorders. The invention provides pharmaceutical compositions comprising said compounds and methods of syntheses thereof.
ENHANCERS OF PROTEIN DEGRADATION
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Page/Page column 25-26; 39, (2011/04/13)
The present invention relates to compounds suitable for modulating huntingtin protein processing and useful for treating or preventing huntingtin-related disorders. The invention provides pharmaceutical compositions comprising said compounds and methods of syntheses thereof.
