68063-55-8

Usage

Physical state

Yellow crystalline solid

Applications

Research and pharmaceutical

Chemical properties

Exhibits properties of both ketones and phenyl compounds

Pharmacological activities

Studied for potential as an anti-inflammatory and antioxidant agent

Safety profile

Not fully elucidated, further studies needed

Suitability for applications

Determination pending further research

Upstream product

• 99-61-6 3-nitro-benzaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 122-84-9 4-methoxybenzyl methyl ketone 
• 126-81-8 dimedone 
• 201230-82-2 carbon monoxide 
• 586-39-0 1-nitro-3-vinyl-benzene 
• 66107-29-7 4-methoxyphenyl triflate 

Downstream Products

• 30437-92-4 3-amino-4'-methoxy-chalcone 
• 1446490-97-6 7,8-dihydro-2-(4-methoxyphenyl)-7,7-dimethyl-4-(3-nitrophenyl)quinolin-5(1H,4H,6H)-one 
• 1210051-85-6 1-(4-methoxyphenyl)-3-(3-nitrophenyl)-3-(phenylthio)propan-1-one 
• 1268494-08-1 C₁₈H₁₇NO₅S 

Relevant academic research and scientific papers

A robust multifunctional ligand-controlled palladium-catalyzed carbonylation reaction in water

A novel, hydrophilic and recyclable methoxypolyethylene glycol (PEG)-modulated s-triazine-based multifunctional Schiff base/N,P-ligand L9 was prepared and used in Pd-catalyzed Heck-type carbonylative coupling reactions, affording diverse chalcone derivatives and 1,4-dicarbonyl esters in good yields.

Imidazole-triazine type compound and preparation method and application thereof

The invention provides an imidazole-triazine type compound which is shown as the formula 3 in the description and a preparation method and application thereof. The method comprises the steps that a triazine compound and an alpha,beta-unsaturated ketone type compound are mixed and added into a solvent, under the existence of a metal copper catalyst and an oxidizing material, the mixed solution is stirred and reacts 5-20 hours under the temperature of 60-150 DEG C, after the reaction is finished, the reacted solution is subjected to post processing, and the imidazole-triazine type compound which is shown as the formula 3 is obtained; the metal copper catalyst is halogenide of the copper or a copper salt; the oxidizing material is a halogen elementary substance. The imidazole-triazine type compound can be applied to prepare antibacterial drugs or antibacterial agents, and the preferred antibacterial drugs are the drugs which inhibit activity of escherichia coli.

A new MCM-41 supported HPF6 catalyst for the library synthesis of highly substituted 1,4-dihydropyridines and oxidation to pyridines: Report of one-dimensional packing towards LMSOMs and studies on their photophysical properties

A new heterogeneous MCM-41 silica supported HPF6 catalyst has been synthesized and characterized using an array of sophisticated analytical techniques like BET, XRD, HRTEM, EDX, 29Si MAS NMR, TGA, FTIR, and pH measurement. The broad

NUCLEAR RECEPTOR MODULATORS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CANCER

Disclosed are compounds which are nuclear receptor modulators that can act as antagonists to the androgen receptor, for example, a compound of Formula I: wherein R1 to R5 and X1 to X5 are as described herein, as well as pharmaceutically acceptable salts, solvates, and stereoisomers thereof. Pharmaceutical compositions comprising such compounds, as well as methods of use, and treatment for cancers, including prostate cancers, other nuclear receptor mediated cancers, and other conditions, are also disclosed.