68064-52-8

Basic information

• Product Name: S-methyl 2-(4-isobutylphenyl)thiopropionate
• Synonyms: S-methyl 2-(4-isobutylphenyl)thiopropionate
• CAS NO: 68064-52-8
• Molecular Weight: 236.378
• Mol File: 68064-52-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: S-methyl 2-(4-isobutylphenyl)thiopropionate(CAS DataBase Reference)
• NIST Chemistry Reference: S-methyl 2-(4-isobutylphenyl)thiopropionate(68064-52-8)
• EPA Substance Registry System: S-methyl 2-(4-isobutylphenyl)thiopropionate(68064-52-8)

Safety Data

• Hazardous Substances Data: 68064-52-8(Hazardous Substances Data)

Upstream product

• 195305-59-0 (4-Isobutyl-phenyl)-bis-methylsulfanyl-thioacetic acid S-methyl ester 
• 197313-98-7 2-(4-isobutyl-phenyl)-2-methylsulfanyl-thiopropionic acid S-methyl ester 

Downstream Products

• 51146-57-7 (R)-ibuprofene 
• 51146-56-6 (S)-ibuprofen 
• 15687-27-1 ibuprofen 

Relevant articles and documents

An interesting synthetic application of S-alkyl (aryl)bis(alkylsulfanyl)thioacetates: General procedure for the preparation of (±)-α-arylpropionic acids

Reported here is a new procedure for the synthesis of α-arylpropionic acids 1 in the racemic form, starting from derivatives of aromatic carboxylic acids 2 (i.e., esters), via 1-aryl-2,2,2-tris(alkylsulfanyl)ethanones 4-6, S-alkyl (aryl)bis(alkylsulfanyl)thioacetates 7-9, S-alkyl α-aryl-α-(alkylsulfanyl)thiopropionates 10-12 and S-alkyl α-arylthiopropionates 13-15. Each stage takes place easily and yields are always high.