68098-76-0Relevant academic research and scientific papers
Synthesis and biological activity of new quinoxaline antibiotics of echinomycin analogues
Kim, Yun Bong,Kim, Yong Hae,Park, Ju Youn,Kim, Soo Kie
, p. 541 - 544 (2004)
Novel quinoxaline antibiotics having the methylenedithioether bridge as an analogue of echinomycin have been synthesized by insertion of methylene moiety between -S-S- bond. The compound 1a shows remarkable cytotoxicities against human tumor various cell
Solution-phase synthesis and biological evaluation of triostin A and its analogues
Hattori, Kozo,Koike, Kota,Okuda, Kensuke,Hirayama, Tasuku,Ebihara, Masahiro,Takenaka, Mei,Nagasawa, Hideko
, p. 2090 - 2111 (2016/02/18)
Triostin A is a biosynthetic precursor of echinomycin which is one of the most potent hypoxia inducible factor 1 (HIF-1) inhibitors. An improved solution-phase synthesis of triostin A on a preparative scale has been achieved in 17.5% total yield in 13 ste
