68104-99-4 Usage
Uses
Used in Pharmaceutical Industry:
4-Cyclopentyl-3-oxo-butyric acid ethyl ester is used as a chemical intermediate for the synthesis of pharmaceuticals, specifically those aimed at treating neurological disorders. Its role in the development of medications is attributed to its ability to serve as a building block in the creation of more complex molecules with therapeutic properties.
Used in Organic Synthesis:
In the field of organic synthesis, 4-Cyclopentyl-3-oxo-butyric acid ethyl ester is employed as a versatile intermediate. It is utilized in the preparation of various organic compounds, contributing to the advancement of chemical research and the development of new materials and substances with diverse applications.
Used in Medicinal Chemistry:
4-Cyclopentyl-3-oxo-butyric acid ethyl ester is used as a key component in medicinal chemistry for its potential to contribute to the discovery and design of new drugs. Its unique structure allows it to be a valuable asset in the synthesis of molecules with specific biological activities, potentially leading to the creation of innovative treatments for various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 68104-99-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,1,0 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 68104-99:
(7*6)+(6*8)+(5*1)+(4*0)+(3*4)+(2*9)+(1*9)=134
134 % 10 = 4
So 68104-99-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H18O3/c1-2-14-11(13)8-10(12)7-9-5-3-4-6-9/h9H,2-8H2,1H3
68104-99-4Relevant academic research and scientific papers
Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABAA receptors
Lager, Erik,Nilsson, Jakob,stergaard Nielsen, Elsebet,Nielsen, Mogens,Liljefors, Tommy,Sterner, Olov
, p. 6936 - 6948 (2008/12/21)
The finding that alkyl 1,4-dihydro-4-oxoquinoline-3-carboxylate and N-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxamide derivatives may be high-affinity ligands at the benzodiazepine binding site of the GABAA receptor, prompted a study of 3-acyl-1,4-dihydro-4-oxoquinoline (3-acyl-4-quinolones). In general, the affinity of the 3-acyl derivatives was found to be comparable with the 3-carboxylate and the 3-carboxamide derivatives, and certain substituents (e.g., benzyl) in position 6 were again shown to be important. As it is believed that the benzodiazepine binding site is situated between an α- and a γ-subunit in the GABAA receptor, selected compounds were tested on the α1β2γ2s, α2β2γ2s and α3β2γ2s GABAA receptor subtypes. The 3-acyl-4-quinolones display various degrees of selectivity for α1- versus α2- and α3-containing receptors, and high-affinity ligands essentially selective for α1 over α3 were developed.
SYNTHESIS OF dl-PENTALENOLACTONES E AND F.
Cane,Thomas
, p. 5295 - 5303 (2007/10/12)
The methyl esters of ( plus or minus )-pentalenolactone E and F have been synthesized by a route based on the intramolecular insertion of an alpha -acylcarbene into an unactivated C-H bond to effect closure of the key fused delta -lactone ring system. Lactone reduction, deketalization, and selective acetalization of the derived lactol provided as a mixture of epimers.
