681138-79-4Relevant academic research and scientific papers
Isoxazoles as Latent Siloxybutadienes: An Easy Entry to Polyfunctionalized Benzene Systems via Diels-Alder Reaction with Acetylenes
Barbero, Asuncion,Pulido, Francisco J.
, p. 401 - 404 (2004)
Base-induced or reductive cleavage of isoxazole rings followed by silylation of the resulting open-chain products affords bis(siloxy)butadienes in high yields. Their synthetic usefulness in the construction of multifunctionalized aromatic systems, via Diels-Alder reactions, is shown. The ability of bis(siloxy)butadienes to undergo deprotonation and reaction with electrophiles is also studied.
