681144-89-8Relevant academic research and scientific papers
Synthesis of new N-isobutyryl-l-cysteine/MEA conjugates: Evaluation of their free radical-scavenging activities and anti-HIV properties in human macrophages
Smietana, Michael,Clayette, Pascal,Mialocq, Patricia,Vasseur, Jean-Jacques,Oiry, Joel
, p. 133 - 140 (2008/09/20)
Four novel N-isobutyryl-l-cysteine/2-mercaptoethylamine (MEA, cysteamine) conjugates have been designed and synthesized. The antioxidant activities of these new series were evaluated by three different free radical scavenging methods (DPPH test, ABTS test
Synthesis and Biological Evaluation in Human Monocyte-Derived Macrophages of N-(N-Acetyl-L-cysteinyl)-S-acetylcysteamine Analogues with Potent Antioxidant and Anti-HIV Activities
Oiry, Jo?l,Mialocq, Patricia,Puy, Jean-Yves,Fretier, Philippe,Dereuddre-Bosquet, Nathalie,Dormont, Dominique,Imbach, Jean-Louis,Clayette, Pascal
, p. 1789 - 1795 (2007/10/03)
We synthesized a series of N-(N-acetyl-L-cysteinyl)-S-acetylcysteamine (10) analogues bearing various acyl groups on thiol cysteine or cysteamine residues, to investigate the structure-activity relationship for pro-GSH and anti-HIV properties in human mac
Novel antioxidants, preparation processes and their uses
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Page 15, (2010/02/08)
The invention concerns a process for preparing compounds of general formula (I) wherein R and R′ represent an alkyl radical or an aryl group; and R″ is hydrogen or a CO—R1 group wherein R1 is an alkyl radical or an aryl group; and wherein these compounds are or not in the thiazolidine form; by protecting the N-acyl-L-cysteine to form an intermediate compound; and then by coupling said intermediate compound with S-acylcysteamine hydrochloride or with thiazolidine.
