68140-75-0

Basic information

• Product Name: 1,1'-(methylimino)bis[3-chloropropan-2-ol]
• Synonyms: 1,1'-(methylimino)bis[3-chloropropan-2-ol];1,1'-(Methylimino)bis(3-chloro-2-propanol);2-Propanol, 1,1'-(methylimino)bis(3-chloro-;Bis(3-chloro-2-hydroxypropyl)methylamine;Einecs 268-814-0
• CAS NO: 68140-75-0
• Molecular Formula: C7H15Cl2NO2
• Molecular Weight: 216.1055
• EINECS: 268-814-0
• Mol File: 68140-75-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,1'-(methylimino)bis[3-chloropropan-2-ol](CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-(methylimino)bis[3-chloropropan-2-ol](68140-75-0)
• EPA Substance Registry System: 1,1'-(methylimino)bis[3-chloropropan-2-ol](68140-75-0)

Safety Data

• Hazardous Substances Data: 68140-75-0(Hazardous Substances Data)

Usage

Chemical structure

1,1'-(methylimino)bis[3-chloropropan-2-ol]

Type of compound

Bisbiguanide

Bacteriostatic

Inhibits the growth of bacteria

Bactericidal

Kills bacteria

Effectiveness

Active against a wide range of microorganisms

Healthcare settings

Skin disinfection

Mouthwash

Prevents oral infections and bad breath

Hand sanitizers

Reduces the spread of germs

Wound cleansers

Promotes wound healing and prevents infection

Mechanism of action

Disrupts the cell membranes of bacteria, leading to their death

Safety

Generally considered safe for use

Potential side effects

Skin irritation or allergic reactions in some individuals

Precautions

Use with caution in individuals with a history of sensitivity to the compound

Upstream product

• 74-89-5 methylamine 
• 106-89-8 epichlorohydrin 

Relevant articles and documents

Synthesis of lipopolyhydroxylalkyleneamines for gene delivery

Various bis(2-hydroxy-3-chloropropyl)alkylamines were synthesized by coupling primary amine with epichlorohydrin and utilized as a monomer to react with ethylenediamine (EDA), N,N′-dimethylethylenediamine (DMEDA), or tetramethylethylenediamine (TMEDA) to generate a series of lipopolyhydroxylalkyleneamines. The number- and weight-average molecular weight (Mn and Mw) and polydispersity index (Mw/M n) of the lipopolyhydroxylalkyleneamines were dependent on reactant solvent and reaction temperature. The compounds with EDA as backbone have better transfection activity and lower toxicity than those with DMEDA and TMEDA as backbone.

Structure and Reactivity of Oxirane Chemical Modifiers for Gelatin

New chemical modifiers for gelatin, glycidylamines, are synthesized.Acid-base properties of glycidylamines and the kinetics of reactions of oxirane compounds with nucleophilic reagents, among them aqueous solution of gelatin, are studied.