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681475-21-8

N2-benzyl-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 681475-21-8 Structure

  • Basic information

    1. Product Name: N2-benzyl-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine
    2. Synonyms:
    3. CAS NO:681475-21-8
    4. Molecular Formula:
    5. Molecular Weight: 330.389
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 681475-21-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N2-benzyl-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine(CAS DataBase Reference)
    10. NIST Chemistry Reference: N2-benzyl-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine(681475-21-8)
    11. EPA Substance Registry System: N2-benzyl-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine(681475-21-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 681475-21-8(Hazardous Substances Data)

681475-21-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 681475-21-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,1,4,7 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 681475-21:
(8*6)+(7*8)+(6*1)+(5*4)+(4*7)+(3*5)+(2*2)+(1*1)=178
178 % 10 = 8
So 681475-21-8 is a valid CAS Registry Number.

681475-21-8Downstream Products

681475-21-8Relevant articles and documents

Antibacterial activity of a series of N2, N4- disubstituted quinazoline-2,4-diamines

Van Horn, Kurt S.,Burda, Whittney N.,Fleeman, Renee,Shaw, Lindsey N.,Manetsch, Roman

, p. 3075 - 3093 (2014)

A series of N2,N4-disubstituted quinazoline-2,4- diamines has been synthesized and tested against multidrug resistant Staphylococcus aureus. A structure-activity and structure-property relationship study was conducted to identify new hit compounds. This study led to the identification of N2,N4-disubstituted quinazoline-2,4- diamines with minimum inhibitory concentrations (MICs) in the low micromolar range in addition to favorable physicochemical properties. Testing of biological activity revealed limited potential for resistance to these agents, low toxicity, and highly effective in vivo activity, even with low dosing regimens. Collectively, these characteristics make this compound series a suitable platform for future development of antibacterial agents.

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