68157-99-3

Basic information

• Product Name: (4R,5R)-5-Methyl-4,5-dihydro-oxazole-4-carboxylic acid dimethylamide
• CAS NO: 68157-99-3
• Molecular Weight: 156.184
• Mol File: 68157-99-3.mol

Chemical Properties

• CAS DataBase Reference: (4R,5R)-5-Methyl-4,5-dihydro-oxazole-4-carboxylic acid dimethylamide(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5R)-5-Methyl-4,5-dihydro-oxazole-4-carboxylic acid dimethylamide(68157-99-3)
• EPA Substance Registry System: (4R,5R)-5-Methyl-4,5-dihydro-oxazole-4-carboxylic acid dimethylamide(68157-99-3)

Safety Data

• Hazardous Substances Data: 68157-99-3(Hazardous Substances Data)

Upstream product

• 68157-98-2 N,N-dimethyl-α-isocyanoacetamide 
• 75-07-0 acetaldehyde 

Relevant articles and documents

ASYMMETRIC ALDOL REACTION OF α-ISOCYANOACETAMIDES WITH ALDEHYDES CATALYZED BY A CHIRAL FERROCENYLPHOSPHINE-GOLD(I) COMPLEX

Aldol reaction of N,N-dialkyl-α-isocyanoacetamides with primary alkyl aldehydes in the presence of 0.5-1 molpercent of a chiral (aminoalkyl)ferrocenylphosphine-gold(I) catalyst proceeded with high enantio- and diastereoselectivity to give trans-5-alkyl-2-oxazoline-4-carboxamides of up to 98.6percent ee, which were converted into optically active threo-β-hydroxyamino acids.