68164-52-3Relevant academic research and scientific papers
Direct asymmetric Michael addition of ketones to chalcones catalyzed by a hydroxyphthalimide derived triazole-pyrrolidine
Kumar, Togapur Pavan,Sattar, Mohammad Abdul,Sarma, Vanka Uma Maheshwara
, p. 1615 - 1619 (2014/01/06)
An efficient protocol for the enantioselective Michael additions of ketones to chalcones catalyzed by a hydroxyphthalimide linked triazole-pyrrolidine derivative has been developed. The corresponding products, 1,5-dicarbonyl compounds, were obtained in good yields with high levels of stereoselectivities under mild reaction conditions employing benzoic acid as an additive.
Direct asymmetric michael additions of ketones to nitroolefins and chalcones catalyzed by a Chiral C2-symmetric pyrrolidine-based tetraamine
Ma, Shijun,Wu, Lulu,Liu, Ming,Wang, Yongmei
, p. 2707 - 2713 (2013/01/15)
C2-Symmetric pyrrolidine-based tetraamine, available from commercially starting materials, showed good catalytic activity for asymmetric Michael additions of ketones to nitroalkenes especially to chalcones. The reactions proceeded to give the corresponding products in good yields and in a highly selective manner.
Pyrrolidine-pyridine base catalysts for the enantioselective Michael addition of ketones to chalcones
Xu, Da-Zhen,Shi, Sen,Liu, Yingjun,Wang, Yongmei
experimental part, p. 9344 - 9349 (2010/01/06)
A series of pyrrolidine-pyridine base organocatalysts have been developed and 3a found to be a highly effective catalyst for the asymmetric Michael addition reactions of ketones to chalcones. The reaction generated the corresponding products 1, 5-diketone
