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Isoquinoline, 3,4-dihydro-3,3-dimethyl-1-phenyl-, also known as 3,3-dimethyl-1-phenyl-3,4-dihydroisoquinoline, is an organic compound with the molecular formula C15H17N. It is a derivative of isoquinoline, a heterocyclic aromatic compound with a benzene ring fused to a pyridine ring. This specific compound features two methyl groups attached to the 3-position and a phenyl group at the 1-position, with a dihydro substitution at the 3,4-positions. It is a colorless to pale yellow solid and is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. The compound is known for its potential applications in the development of drugs targeting the central nervous system and other therapeutic areas.

6818-67-3

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6818-67-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6818-67-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,1 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 6818-67:
(6*6)+(5*8)+(4*1)+(3*8)+(2*6)+(1*7)=123
123 % 10 = 3
So 6818-67-3 is a valid CAS Registry Number.

6818-67-3Downstream Products

6818-67-3Relevant academic research and scientific papers

Synthesis, crystal structure, molecular docking studies and biological evaluation of aryl substituted dihydroisoquinoline imines as a potent angiotensin converting enzyme inhibitor

Selmi, Awatef,Aydi, Rihab,Kammoun, Omar,Bougatef, Hajer,Bougatef, Ali,Miled, Nabil,Alghamdi, Othman A.,Kammoun, Majed

, (2021)

The different functionalities of imine group found in many compounds are of important biological activity. Since, the development of novel imines is biologically encouraged, this study aims to develop a straightforward synthesis pathway of dihydroisoquino

Synthesis and reactivity of new dihydroisoquinoline-derived oxaziridines

Selmi, Awatef,Aydi, Rihab,Mosset, Paul,Grée, René,Kammoun, Majed

, p. 108 - 120 (2019/04/17)

N-Alkyl oxaziridines react as oxygenating reagents in the presence of a nucleophile. In this work, we describe the synthesis of new dihydroisoquinoline oxaziridines, and their reactivity in an acid-promoted reaction both in presence and in absence of sulf

Intervention of Phenonium Ion in Ritter Reactions

Ho, Tse-Lok,Chein, Rong-Jie

, p. 591 - 592 (2007/10/03)

The transformation of phenylethyl chloride to 3,4-dihydroisoquinolines is shown to proceed via phenonium ion. The evidence comes from a study of dideuterated analogue 4, and the monomethylated and dimethylated compounds 2 and 3.

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