681848-52-2

Upstream product

• 681848-63-5 2-(2-tert-butoxycarbonylamino-4-methylsulfanyl-butyryl)-heptanedioic acid 7-ethyl ester 1-methyl ester 
• 129081-62-5 4-tert-butoxycarbonylamino-6-methylsulfanyl-3-oxo-hexanoic acid methyl ester 
• 41302-32-3 ethyl 5-iodopentanoate 
• 2488-15-5 N-tert-butoxycarbonyl-L-methionine 
• 681848-50-0 7,8-bis-benzyloxycarbonylamino-10-methylsylfanyl-decanoic acid methyl ester 
• 681848-65-7 8-tert-butoxycarbonylamino-10-methylsulfanyl-7-oxo-decanoic acid methyl ester 

Relevant academic research and scientific papers

Inhibitors of biotin biosynthesis as potential herbicides

Isosteric derivatives and analogues of the 7-keto-8-aminopelargonic acid (KAPA), 7,8-diaminopelargonic acid (DAPA) and desthiobiotin (DTB) vitamer intermediates involved in the biosynthetic pathway of biotin were prepared and evaluated as potential herbicides. The most active compound was desmethyl-KAPA which displayed a GR50 (concentration of the active compound that causes a 50% growth inhibition) value of 8 ppm, where values 2 showed moderate activity.