68185-97-7

Upstream product

• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 
• 618-46-2 m-Chlorobenzoyl chloride 
• 76943-83-4 [Dibromo-(3-chloro-phenyl)-methyl]-trimethyl-silane 

Downstream Products

• 127182-91-6 (3-chlorothiobenzoyl)trimethylsilane 
• 1066-40-6 Trimethylsilanol 
• 587-04-2 m-Chlorobenzaldehyde 
• 865189-98-6 6-chloro-3-(p-tolyl)-2,3-dihydro-1H-inden-1-one 
• 34966-50-2 methyl 2-(3-chlorophenyl)-2-oxoacetate 
• 38925-71-2 β-(m-chlorbenzamido)ethylbenzol 
• 127182-93-8 (E)-(3-chlorothiobenzoyl)trimethylsilane S-oxide 
• 127182-94-9 (E)-(3-chlorophenyl)methanethial S-oxide 
• 23958-24-9 trans-1,2-bis-(3-chlorophenyl)ethene 
• 20101-53-5 (Z)-1,2-bis(3-chlorophenyl)ethene 

Relevant academic research and scientific papers

Visible-Light-Induced Catalyst-Free Carboxylation of Acylsilanes with Carbon Dioxide

Intermolecular carbon-carbon bond formation between acylsilanes and carbon dioxide (CO2) was achieved by photoirradiation under catalyst-free conditions. In this reaction, siloxycarbenes generated by photoisomerization of the acylsilanes added to the C═O bond of CO2 to give α-ketocarboxylates, which underwent hydrolysis to afford α-ketocarboxylic derivatives in good yields. Control experiments suggest that the generated siloxycarbene is likely to be from the singlet state (S1) of the acylsilane and the addition to CO2 is not in a concerted manner.

Chemoselective Amide-Forming Ligation Between Acylsilanes and Hydroxylamines Under Aqueous Conditions

We report the facile amide-forming ligation of acylsilanes with hydroxylamines (ASHA ligation) under aqueous conditions. The ligation is fast, chemoselective, mild, high-yielding and displays excellent functional-group tolerance. Late-stage modifications of an array of marketed drugs, peptides, natural products, and biologically active compounds showcase the robustness and functional-group tolerance of the reaction. The key to the success of the reaction could be the possible formation of the strong Si?O bond via a Brook-type rearrangement. Given its simplicity and efficiency, this ligation has the potential to unfold new applications in the areas of medicinal chemistry and chemical biology.

Ruthenium-Catalyzed Brook Rearrangement Involved Domino Sequence Enabled by Acylsilane-Aldehyde Corporation

A ruthenium-catalyzed [1,2]-Brook rearrangement involved domino sequence is presented to prepare highly functionalized silyloxy indenes with atomic- and step-economy. This domino reaction is triggered by acylsilane-directed C-H activation, and the aldehyde controlled the subsequent enol cyclization/Brook Rearrangement other than β-H elimination. The protocol tolerates a broad substitution pattern, and the further synthetic elaboration of silyloxy indenes allows access to a diverse range of interesting indene and indanone derivatives.

DENTAL COMPOSITION

The present invention relates to a dental composition comprising a specific polymerization initiator system comprising a compound having an acylsilyl- or acylgermanyl-group. The present invention also relates the use of the compound having an acylsilyl- o

DENTAL COMPOSITION

Dental composition comprising (a) a homogeneous phase comprising monomer combinations (i) and (ii), (i) and (iii), (ii) and (iii), or (i), (ii) and (iii), or comprising monomer (iii), wherein (i) represents one or more compounds having one or more radical

THE CONVERSION OF α,α-DIBROMOBENZYLSILANES INTO ACYLSILANES ON SILICA GEL

Acylsilanes may be prepared in high yield by treating α,α-dibromobenzylsilanes with silica gel