681851-33-2

Basic information

• Product Name: 4-Morpholinecarboxylic acid, 3-[[(phenylmethyl)thio]methyl]-, 2,2,2-trichloroethyl ester, (3S)-
• CAS NO: 681851-33-2
• Molecular Formula: C15H18Cl3NO3S
• Molecular Weight: 398.738
• Mol File: 681851-33-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Morpholinecarboxylic acid, 3-[[(phenylmethyl)thio]methyl]-, 2,2,2-trichloroethyl ester, (3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Morpholinecarboxylic acid, 3-[[(phenylmethyl)thio]methyl]-, 2,2,2-trichloroethyl ester, (3S)-(681851-33-2)
• EPA Substance Registry System: 4-Morpholinecarboxylic acid, 3-[[(phenylmethyl)thio]methyl]-, 2,2,2-trichloroethyl ester, (3S)-(681851-33-2)

Safety Data

• Hazardous Substances Data: 681851-33-2(Hazardous Substances Data)

Upstream product

• 681851-31-0 (S)-4-(phenylmethyl)-3-{[(phenylmethyl)sulfanyl]methyl}morpholine 
• 17341-93-4 2,2,2-Trichloroethyl chloroformate 
• 681851-29-6 (S)-3-(bromomethyl)-4-(phenylmethyl)morpholine 
• 106973-40-4 ethyl (S)-5-oxo-4-(phenylmethyl)morpholine-3-carboxylate 
• 106973-37-9 (3S)-5-oxo-4-(phenylmethyl)-3-morpholinecarboxylic acid 
• 101376-26-5 (3R)-4-benzyl-3-(hydroxymethyl)-morpholine 

Downstream Products

• 681851-35-4 (S)-3-{[(phenylmethyl)sulfanyl]methyl}morpholine 

Relevant articles and documents

Properties and Reactions of Substituted 1,2-Thiazetidine 1,1-Dioxides: Chiral Mono- and Bicyclic 1,2-Thiazetidine 1,1-Dioxides from α-Amino Acids

New chiral mono- and bicyclic β-sultams, valuable building blocks for drug synthesis, have been prepared from L-Ala, L-Val, L-Leu, L-Ile, L-Phe, L-Cys, L-Ser, L-Thr, and D-penicillamine by transformation of the COOH group into a methylsulfonyl chloride function, followed by cyclization under basic conditions. Selected properties, derivatives, and reactions of the β-sultams are described.