68227-69-0 Usage
Uses
Used in Pharmaceutical Synthesis:
Phenyl-2-aminobenzenesulfonate is used as an intermediate in the synthesis of various pharmaceuticals for its ability to facilitate the formation of complex organic molecules, contributing to the development of new drugs and therapeutic agents.
Used in Organic Synthesis:
As a reagent in organic synthesis, Phenyl-2-aminobenzenesulfonate is used for its capacity to participate in a variety of chemical reactions, aiding in the creation of diverse organic compounds.
Used in Dye and Pigment Production:
Phenyl-2-aminobenzenesulfonate is used as an intermediate in the production of dyes and pigments, enabling the creation of a broad spectrum of colors for various applications in industries such as textiles, plastics, and printing.
Used in Research and Development:
In the field of research and development, Phenyl-2-aminobenzenesulfonate is used to explore its potential pharmacological properties and biological activities, with the aim of discovering new applications in medicine and other fields.
Used in Chemical Reactions:
Phenyl-2-aminobenzenesulfonate is utilized as a reagent in various chemical reactions, playing a crucial role in the synthesis of a wide array of organic compounds, thus contributing to the advancement of chemical science and technology.
Check Digit Verification of cas no
The CAS Registry Mumber 68227-69-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,2,2 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 68227-69:
(7*6)+(6*8)+(5*2)+(4*2)+(3*7)+(2*6)+(1*9)=150
150 % 10 = 0
So 68227-69-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO3S/c13-11-8-4-5-9-12(11)17(14,15)16-10-6-2-1-3-7-10/h1-9H,13H2
68227-69-0Relevant articles and documents
Catalysis of Sulfonate Ester Hydrolysis by Intramolecular Amide Group Assistance.
Thea, Sergio,Guanti, Giuseppe,Hopkins, Andrew R.,Williams, Andrew
, p. 3336 - 3341 (2007/10/02)
Kinetics of the alkaline hydrolysis of aryl 2-(acylamino)benzenesulfonates (1, X=OAr) obey the equation kobs=(Ka+kb->/(1++>/Ko).Hammett equations correlate the parameters ka, kb, and Ka for variation in both amido and leaving phenolate substituents.The values and sign of the ρ values together with entropy of activation data, reactivity trapping, and oxygen-18 incorporation are consistent with the formation of an intermediate benzoxathiazine S,S-dioxide (2).The ka term involves intramolecular attack of the amido anion.The kb term is consistent with a specific anion effect on ka.Regular bimolecular BAc2 mechanisms for ka and kb are not consistent with the high observed reactivity of these parameters.
The Pyrolysis of 2-Azidobenzoates. A New Synthesis of Carbazoles and Other N-Heterocycles
Clancy, Michael G.,Hesabi, Massoud M.,Meth-Cohn, Otto
, p. 429 - 434 (2007/10/02)
The spray pyrolysis of aryl 2-azidobenzoates yields carbazoles, involving a rearrangement whereby the nitrogen of the product is attached to the aryl 1-carbon, a process involving a spiro 6-membered intermediate.When the aryl ortho-positions were both alkyl substituted the product was ab acridan instead.With an ortho-carboxylate, acridone formation competed with that of carbazole.When the CO-O group of the substrate was replaced by O-CO, CO-S, CO-NPh, or SO2-O the pyrolysis was ineffective.Benzyl 2-azidobenzoates, however, pyrolysed to yield 1-benzyl-2,1-benzisoxazolones by an unprecedented C-O insertion reaction of the intermediate nitrene.
