68236-26-0

Basic information

• Product Name: N-(2-BROMOTHIOPHEN-5-YL)-ACETAMIDE
• Synonyms: N-(5-BROMO-THIOPHENE-2-YL)-ACETAMIDE;N-(2-BROMOTHIOPHEN-5-YL)-ACETAMIDE;2-AcetaMido-5-broMothiophene;N-(5-BroMothiophen-2-yl)acetaMide;N-(5-bromo-2-thienyl)Acetamide;N-(5-Bromothiophen-2-yl)
• CAS NO: 68236-26-0
• Molecular Formula: C₆H₆BrNOS
• Molecular Weight: 220.08694
• Mol File: 68236-26-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 135-136 °C
• Boiling Point: 357.0±27.0 °C(Predicted)
• Appearance: /
• Density: 1.717±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 14.02±0.70(Predicted)
• CAS DataBase Reference: N-(2-BROMOTHIOPHEN-5-YL)-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-BROMOTHIOPHEN-5-YL)-ACETAMIDE(68236-26-0)
• EPA Substance Registry System: N-(2-BROMOTHIOPHEN-5-YL)-ACETAMIDE(68236-26-0)

Safety Data

• Hazardous Substances Data: 68236-26-0(Hazardous Substances Data)

Usage

General Description

N-(2-bromothiophen-5-yl)-acetamide, also known as 2-Bromo-5-(2-thienyl)acetamide, is a chemical compound with the molecular formula C6H6BrNOS. It is an amide derivative of 2-bromothiophene-5-carboxylic acid, and it is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. N-(2-BROMOTHIOPHEN-5-YL)-ACETAMIDE is a white solid with a molecular weight of 216.09 g/mol. It is primarily used in the research and development of various organic and pharmaceutical compounds, and it is often employed as a reagent in organic synthesis. It is important to handle this chemical with caution, as it can be hazardous if not used properly.

Upstream product

• 5370-25-2 2-Acetyl-5-bromothiophene 
• 74322-99-9 1-(5-bromothiophen-2-yl)ethanone oxime 
• 13195-50-1 2-bromo-5-nitrothiophene 
• 108-24-7 acetic anhydride 
• 98453-21-5 (1E)-1-(5-bromothiophen-2-yl)ethanone oxime 
• 943321-89-9 1,1-dimethylethyl (5-bromo-2-thienyl)carbamate 

Downstream Products

• 68236-35-1 6-bromo-2-chlorothieno<2,3-b>pyridine 
• 1599475-27-0 C₁₃H₈BrF₂NO₂S 
• 1599475-23-6 C₁₃H₇BrF₃NO₂S 
• 68236-39-5 6-bromo-2-phenylthiothieno<2,3-b>pyridine 
• 62226-18-0 6-chlorothieno[2,3-b]pyridine 

Relevant articles and documents

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An efficient catalytic method for the Beckmann rearrangement of ketoximes to amides and aldoximes to nitriles mediated by propylphosphonic anhydride (T3P)

An efficient method for the Beckmann rearrangement of ketoximes to amides mediated by a catalytic amount (15 mol %) of propylphosphonic anhydride (T3P) is described. Aldoximes underwent second order Beckmann rearrangement to provide the corresponding nitriles in excellent yields on reacting with T3P (15 mol %) at room temperature. The main advantages of this environmentally friendly protocol include procedural simplicity, and particularly ease of isolation of the products.